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Health-related quality of life of type 2 diabetes patients hospitalized for a diabetes-related complication

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Abstract

Purpose

To estimate the health-related quality of life (HRQoL) of type 2 diabetes (T2DM) inpatients hospitalized for a complication in China and to explore the associated factors.

Methods

This was a cross-sectional study. T2DM inpatients (aged ≥ 18 years) hospitalized for a complication, including ischemic heart disease (IHD), acute myocardial infarction (AMI), congestive heart failure (CHF), stroke, impaired vision, end-stage renal disease (ESRD), ulcer, and amputation were recruited from a tertiary hospital in China from January to May 2017. The EuroQoL-5 dimensions were used to measure HRQoL. A one-way analysis of variance and a multivariate regression analysis were performed.

Results

Eight hundred and two T2DM inpatients hospitalized for a complication were included. The mean age was 62.67 years, and 43% of the inpatients were female. The mean utility-based HRQoL was 0.562 (95% CI 0.548, 0.577). The utility varied significantly between the complications: IHD = 0.620 (95% CI 0.597, 0.642), AMI = 0.434 (95% CI 0.394, 0.473), CHF = 0.471 (95% CI 0.433, 0.510), stroke = 0.472 (95% CI 0.436, 0.508), impaired vision = 0.714 (95% CI 0.692, 0.737), ESRD = 0.693 (95% CI 0.670, 0.717), ulcer = 0.431 (95% CI 0.375, 0.487), and amputation = 0.395 (95% CI 0.341, 0.448). Inpatients with a complication, who were female, and who had no daily exercise had a lower HRQoL.

Conclusions

The HRQoL of T2DM inpatients with a complication was considerably impaired. Our estimates provide supplementary data for public health and cost-effectiveness modeling, and increase the breadth of knowledge of HRQoL in T2DM.

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Acknowledgements

The authors thank Xuemei Zhen, Jingming Wei, Can Zhao, Qilong Gao, Mengfei Yu, Run Liang and Tian Sang (Zhejiang University School of Medicine, Hangzhou, China), and the doctors and nurses (Shandong Provincial Hospital affiliated to Shandong University, Jinan, China) for their help in collecting data.

Funding

No funding was received for this study. The corresponding author had full access to all the data in the study and had final responsibility for the decision to submit for publication.

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Authors and Affiliations

  1. Centre for Health Policy Studies, School of Public Health, School of Medicine, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, Zhejiang, China

    Shuyan Gu, Xiaoqian Hu, Yuxuan Gu, Xueshan Sun & Hengjin Dong

  2. Center for Health Policy and Management Studies, School of Government, Nanjing University, Nanjing, Jiangsu, China

    Shuyan Gu

  3. Health Insurance Office, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China

    Xiaoyong Wang

  4. Department of Global Health Management and Policy, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA

    Lizheng Shi

  5. Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China

    Qiuying Sun

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  1. Shuyan Gu
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Contributions

The authors all made substantial contributions to the analysis. SG designed the study, researched and analyzed the data, and wrote, reviewed and edited the manuscript. HD designed the study, and reviewed and edited the manuscript. XW and XH researched and analyzed the data. LS reviewed and edited the manuscript. QS, YG, and XS researched the data.

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Correspondence to Hengjin Dong.

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All procedures performed in studies involving human participants were in accordance with the Ethical Standards of the Institutional and/or National Research Committee (Medical Faculty Ethics Committee of Zhejiang University + ZGL201606-2) and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Gu, S., Wang, X., Shi, L. et al. Health-related quality of life of type 2 diabetes patients hospitalized for a diabetes-related complication. Qual Life Res 29, 2695–2704 (2020). https://doi.org/10.1007/s11136-020-02524-3

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