Abstract
Background
Quality of life and psychological responses to transplantation are constructs used to assess various psychosocial aspects after organ transplantation. The purpose of this study is to compare physical, psychological, social, and environmental quality of life between recipients of four organs: liver, lung, heart, and kidney.
Methods
In order to compare the four types of quality of life and emotional responses post-transplant, HRQOL and TxEQ questionnaires were administered to 427 transplant recipients.
Results
Heart and liver recipients report significantly higher health-related quality of life than lung and kidney recipients. Heart and lung patients report significantly fewer concerns and worries than liver and kidney patients. New additional variables were explored in our study: psychological connection to the living donor/deceased donor's family and commitment to them. We also found that heart recipients feel their personality traits changed, postoperative.
Conclusions
The contribution of our study was the finding that ethno-religious and psychosocial variables have a positive effect on four dimensions of HRQOL. It may be useful to design psychological support interventions specifically adapted to patients after organ transplantation that aim at enhancing patients' HRQOL and alleviating negative emotional responses.
This is a preview of subscription content, access via your institution.


References
WHO. WHOQOL-BREF: Introduction, administration, scoring and generic version of the assessment; Field trial version. Geneva: World Health Organization; 1996. Retrieved July 4, 2019, from https://www.who.int/mental_health/media/en/76.pdf.
Sarac, N., Ambühl, P., Irani, S., et al. (2008). Psychological response and quality of life after transplantation: A comparison between heart, lung, liver and kidney recipients. Swiss Medical Weekly,138(33–34), 477–483.
Revicki, D. A., Osoba, D., Faiclough, D., et al. (2000). Recommendations on health-related quality of life research to support labeling and promotional claims in United States. Quality of Life Research,9, 887–900.
Trevizan, F. B., Miyazaki, M. C. D. O. S., Silva, Y. L. W., & Roque, C. M. W. (2017). QOL, depression, anxiety and coping after heart transplantation. Brazilian Journal of Cardiovascular Surgery,32(3), 162–170.
Liu, H., Feurer, I. D., Dwyer, K., et al. (2009). Effects of clinical factors on psychosocial variables in renal transplant recipients. Journal of Advanced Nursing,65(12), 2585–2596.
Thabut, G., & Mal, H. (2017). Outcomes after lung transplantation. Journal of Thoracic Disease,9(8), 2684.
Bleisch, B., Schuurmans, M. M., Klaghofer, R., et al. (2019). Health-related quality of life and stress-related post-transplant trajectories of lung transplant recipients: A three-year follow-up of the Swiss Transplant Cohort Study. Swiss Medical Weekly. https://doi.org/10.4414/smw.2019.20019.
McAdams-DeMarco, M. A., Olorundare, I. O., Ying, H., et al. (2018). Frailty and post kidney transplant health-related quality of life. Transplantation,102(2), 291.
Villeneuve, C., Laroche, M. L., Essig, M., et al. (2016). Evolution and determinants of health-related quality-of-life in kidney transplant patients over the first 3 years after transplantation. Transplantation,100(3), 640–647.
Doering, L. V., Chen, B., Deng, M., et al. (2018). Perceived control and health-related quality of life in heart transplant recipients. European Journal of Cardiovascular Nursing,17(6), 513–520.
Ågren, S., Sjöberg, T., Ekmehag, B., et al. (2017). Psychosocial aspects before and up to 2 years after heart or lung transplantation: Experience of patients and their next of kin. Clinical Transplantation,31(3), e12905.
Burra, P., & Ferrarese, A. (2019). Health-related quality of life in liver transplantation: Another step forward. Transplant International,32(8), 792–793.
Ziegelmann, J. P., Griva, K., Hankins, M., et al. (2002). The Transplant Effects Questionnaire (TxEQ): The development of a questionnaire for assessing the multidimensional outcome of organ transplantation—Example of end stage renal disease (ESRD). British Journal of Health Psychology,7(4), 393–408.
Muehrer, R. J., & Becker, B. N. (2005). Psychosocial factors in patients with chronic kidney disease: Life after transplantation: New transitions in quality of life and psychological distress. Seminars in Dialysis,18(2), 124–131.
Achille, M. A., Ouellette, A., Fournier, S., Vachon, M., & Hébert, M. J. (2006). Impact of stress, distress and feelings of indebtedness on adherence to immunosuppressants following kidney transplantation. Clinical Transplants,20(3), 301–306.
McAdams-DeMarco, M.A., Olorundare, I.O., Ying, H., Warsame, F., Haugen, C.E., Hall, R., ... & Segev, D.L.(2018) Frailty and postkidney transplant health-related quality of life. Transplantation. 102(2), 291.
Taskintuna, N., & Özçürümez, G. (2011). End-stage renal disease and psychological trauma: Shame and guilt in hemodialysis patients, transplantation recipient and donor candidates, and controls. Archives of Neuropsychiatry,48(4), 249–254.
Funding
The research project received no funding.
Author information
Authors and Affiliations
Contributions
PA and YBC participated in research design. YBC PA and MT participated in the writing of the paper. MT participated in the performance of the research. YBC participated in the data analysis of the project. MT and YBC participated in data analysis. PA and MT reviewed the draft of the paper. YBC and MT approved the final draft of the paper.
Corresponding author
Ethics declarations
Conflict of interest
The authors declare thay they have no conflicts of interest.
Ethical approval
Ethical approval was obtained from the IRB of the Academic College of Tel Aviv Jaffa.
Informed consent
All participants signed an informed consent form.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Tarabeih, M., Bokek-Cohen, Y. & Azuri, P. Health-related quality of life of transplant recipients: a comparison between lung, kidney, heart, and liver recipients. Qual Life Res 29, 1631–1639 (2020). https://doi.org/10.1007/s11136-020-02434-4
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11136-020-02434-4
Keywords
- Heart transplantation
- Kidney transplantation
- Liver transplantation
- Lung transplantation
- Quality of life