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Quality of Life Research

, Volume 28, Issue 3, pp 567–592 | Cite as

A systematic review of randomised controlled trials evaluating the use of patient-reported outcome measures (PROMs)

  • S. IshaqueEmail author
  • J. Karnon
  • G. Chen
  • R. Nair
  • A. B. Salter
Review

Abstract

Background

Patient-reported outcome measures (PROMs) could play an important role in identifying patients’ needs and goals in clinical encounters, improving communication and decision-making with clinicians, while making care more patient-centred. Comprehensive evidence that PROMS are an effective intervention is lacking in single randomised controlled trials (RCTs).

Methods

A systematic search was performed using controlled vocabulary related to the terms: clinical care setting and patient-reported outcome. English language studies were included if they were a RCT with a PROM as an intervention in a patient population. Included studies were analysed and their methodologic quality was appraised using the Cochrane Risk of Bias tool. The protocol was registered with PROSPERO (CRD42016034182).

Results

Of 4302 articles initially identified, 115 underwent full-text review resulting in 22 studies reporting on 25 comparisons. The majority of included studies were conducted in USA (11), among cancer patients (11), with adult participants only (20). Statistically significant and robust improvements were reported in the pre-specified outcomes of the process of care (2) and health care (3). Additionally, five, eight and three statistically significant but possibly non-robust findings were reported in the process of care, health and patient satisfaction outcomes, respectively.

Conclusions

Overall, studies that compared PROM to standard care either reported a positive effect or were not powered to find pre-specified differences. There is justification for the use of a PROM as part of standard care, but further adequately powered studies on their use in different contexts are necessary for a more comprehensive evidence base.

Keywords

Patient-reported outcome measures PROMs Health-related quality of life HRQL HRQoL Quality of life QOL Patient outcomes Patient-reported outcomes Clinical care 

Abbreviations

± PROM studies

Studies that compared patient completion of a PROM with standard care in the control group

PROM ± summary studies

Studies in which all patients completed a PROM and compared the presentation of PROM summary scores to clinicians vs. no presentation of summary scores

FDA

Food and drug administration

HRQL

Health-related quality of life

PRO

Patient-reported outcomes

PROM

Patient-reported outcome measure

QOL

Quality of life

RCT

Randomised controlled trial

SR

Systematic review

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This review does not contain any studies with human participants performed by any of the authors.

Informed consent

Informed Consent was not applicable to this review as no primary data were collected.

Supplementary material

11136_2018_2016_MOESM1_ESM.docx (51 kb)
Supplementary material 1 (DOCX 50 KB)

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Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  1. 1.School of Public HealthUniversity of AdelaideAdelaideAustralia
  2. 2.Centre for Health Economics, Monash Business SchoolMonash UniversityClaytonAustralia
  3. 3.School of DentistryUniversity of AdelaideAdelaideAustralia

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