Quality of Life Research

, Volume 25, Issue 4, pp 823–833 | Cite as

Linkage between the PROMIS® pediatric and adult emotional distress measures

  • Bryce B. ReeveEmail author
  • David Thissen
  • Darren A. DeWalt
  • I-Chan Huang
  • Yang Liu
  • Brooke Magnus
  • Hally Quinn
  • Heather E. Gross
  • Pamela A. Kisala
  • Pengsheng Ni
  • Stephen Haley
  • M. J. Mulcahey
  • Susie Charlifue
  • Robin A. Hanks
  • Mary Slavin
  • Alan Jette
  • David S. Tulsky



Research studies that measure health-related quality of life (HRQOL) in both children and adults and longitudinal studies that follow children into adulthood need measures that can be compared across these age groups. This study links the PROMIS pediatric and adult emotional distress measures using data from participants with diverse health conditions and disabilities.


Analyses were conducted and compared in two separate samples to confirm the stability of results. One sample (n = 874) included individuals aged 14–20 years with special health care needs and who require health services. The other sample (n = 641) included individuals aged 14–25 years who have a physical or cognitive disability. Participants completed both PROMIS pediatric and adult measures. Item response theory-based scores were linked using the linear approximation to calibrated projection.


The estimated latent-variable correlation between pediatric and adult PROMIS measures ranged from 0.87 to 0.94. Regression coefficients β 0 (intercept) and β 1 (slope), and mean squared error are provided to transform scores from the pediatric to the adult measures, and vice versa.


This study used a relatively new linking method, calibrated projection, to link PROMIS pediatric and adult measure scores, thus expanding the use of PROMIS measures to research that includes both populations.


PROMIS Pediatrics Patient-reported outcomes Item response theory Linkage Emotional distress 



PROMIS® was funded with cooperative agreements from the National Institutes of Health (NIH) Common Fund Initiative Northwestern University, PI: David Cella, PhD, U54AR057951, U01AR052177; Northwestern University, PI: Richard C. Gershon, PhD, U54AR057943; American Institutes for Research, PI: Susan (San) D. Keller, PhD, U54AR057926; State University of New York, Stony Brook, PIs: Joan E. Broderick, PhD and Arthur A. Stone, PhD, U01AR057948, U01AR052170; University of Washington, Seattle, PIs: Heidi M. Crane, MD, MPH, Paul K. Crane, MD, MPH, and Donald L. Patrick, PhD, U01AR057954; University of Washington, Seattle, PI: Dagmar Amtmann, PhD, U01AR052171; University of North Carolina, Chapel Hill, PI: Harry A. Guess, MD, PhD (deceased), Darren A. DeWalt, MD, MPH, Bryce B. Reeve, PhD, U01AR052181; Children’s Hospital of Philadelphia, PI: Christopher B. Forrest, MD, PhD, U01AR057956; Stanford University, PI: James F. Fries, MD, U01AR052158; Boston University, PIs: Alan Jette, PT, PhD, Stephen M. Haley, PhD (deceased), and David Scott Tulsky, PhD (University of Michigan, Ann Arbor), U01AR057929; University of California, Los Angeles, PIs: Dinesh Khanna, MD (University of Michigan, Ann Arbor) and Brennan Spiegel, MD, MSHS, U01AR057936; University of Pittsburgh, PI: Paul A. Pilkonis, PhD, U01AR052155; Georgetown University, PIs: Carol. M. Moinpour, PhD (Fred Hutchinson Cancer Research Center, Seattle) and Arnold L. Potosky, PhD, U01AR057971; Children’s Hospital Medical Center, Cincinnati, PI: Esi M. Morgan DeWitt, MD, MSCE, U01AR057940; University of Maryland, Baltimore, PI: Lisa M. Shulman, MD, U01AR057967; and Duke University, PI: Kevin P. Weinfurt, PhD, U01AR052186). NIH Science Officers on this project have included Deborah Ader, PhD, Vanessa Ameen, MD (deceased), Susan Czajkowski, PhD, Basil Eldadah, MD, PhD, Lawrence Fine, MD, DrPH, Lawrence Fox, MD, PhD, Lynne Haverkos, MD, MPH, Thomas Hilton, PhD, Laura Lee Johnson, PhD, Michael Kozak, PhD, Peter Lyster, PhD, Donald Mattison, MD, Claudia Moy, PhD, Louis Quatrano, PhD, Bryce B. Reeve, PhD, William Riley, PhD, Peter Scheidt, MD, Ashley Wilder Smith, PhD, MPH, Susana Serrate-Sztein, MD, William Phillip Tonkins, DrPH, Ellen Werner, PhD, Tisha Wiley, PhD, and James Witter, MD, PhD. The contents of this article uses data developed under PROMIS. These contents do not necessarily represent an endorsement by the US Federal Government or PROMIS. See for additional information on the PROMIS® initiative.

Compliance with ethical standards

Conflict of interest

Drs. DeWalt and Tulsky were unpaid members of the Board of Directors for the PROMIS Health Organization (PHO) during the conduct of this study. Drs. Reeve and Tulsky were unpaid members of the Board of Directors for the PHO during the preparation of this manuscript. The remaining authors have no financial relationships or conflicts of interest relevant to this study to disclose.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Research involving human participants

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.


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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Bryce B. Reeve
    • 1
    • 2
    Email author
  • David Thissen
    • 3
  • Darren A. DeWalt
    • 4
  • I-Chan Huang
    • 5
    • 6
  • Yang Liu
    • 7
  • Brooke Magnus
    • 3
  • Hally Quinn
    • 3
  • Heather E. Gross
    • 2
  • Pamela A. Kisala
    • 8
  • Pengsheng Ni
    • 9
  • Stephen Haley
    • 9
  • M. J. Mulcahey
    • 10
  • Susie Charlifue
    • 11
  • Robin A. Hanks
    • 12
  • Mary Slavin
    • 9
  • Alan Jette
    • 9
  • David S. Tulsky
    • 8
  1. 1.Department of Health Policy and Management, Gillings School of Global Public HealthUniversity of North Carolina at Chapel HillChapel HillUSA
  2. 2.Cecil G. Sheps Center for Health Services ResearchUniversity of North Carolina at Chapel HillChapel HillUSA
  3. 3.Department of Psychology and NeuroscienceUniversity of North Carolina at Chapel HillChapel HillUSA
  4. 4.Division of General Medicine and Clinical Epidemiology, Cecil G. Sheps Center for Health Services ResearchUniversity of North Carolina at Chapel HillChapel HillUSA
  5. 5.Department of Health Outcomes and Policy, College of MedicineUniversity of FloridaGainesvilleUSA
  6. 6.Department of Epidemiology and Cancer ControlSt. Jude Children’s Research HospitalMemphisUSA
  7. 7.School of Social SciencesHumanities, and Arts University of CaliforniaMercedUSA
  8. 8.Center for Assessment Research and Translation, Department of Physical Therapy, College of Health SciencesUniversity of DelawareNewarkUSA
  9. 9.Health and Disability Research InstituteBoston University School of Public HealthBostonUSA
  10. 10.Department of Occupational Therapy, School of Health ProfessionsThomas Jefferson UniversityPhiladelphiaUSA
  11. 11.Craig HospitalEnglewoodUSA
  12. 12.Wayne State University School of MedicineDetroitUSA

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