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Validating the Migraine-Specific Quality of Life Questionnaire v2.1 (MSQ) in Italian inpatients with chronic migraine with a history of medication overuse

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Abstract

Purpose

The purpose of the study is to assess validity, reliability and factor structure of the Italian version of Migraine-Specific Quality of Life Questionnaire v2.1 (MSQ) in patients suffering from chronic migraine (CM) with a history of medication overuse (MO).

Methods

Patients were enroled at hospital admission for withdrawal from MO. Factor analysis was used to confirm the latent structure of the MSQ. Reliability was measured with Cronbach’s alpha coefficient, item-total correlation and inter-item correlation. Construct validity was assessed with Pearson’s coefficient and known-group analysis.

Results

The three-factor structure is basically confirmed. Cronbach’s alpha varied between 0.85 and 0.92; item-total correlations were on average higher than 0.70; average inter-item correlation ranged between 0.63 and 0.65. Correlations were all significant; known-group analysis shows that MSQ score was lower consistently with disease severity.

Conclusions

Our findings confirm the factor structure, reliability and validity of the MSQ and expand results of previous validation studies to the Italian language and to a group of patients with severe CM requiring withdrawal treatment for MO.

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Acknowledgments

This study was and independent examination on disability and quality of life associated with chronic migraine (DIS.CHRONIC), sponsored by the Neurological Institute C. Besta IRCCS Foundation.

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Authors and Affiliations

  1. Neurology, Public Health and Disability Unit, Neurological Institute C. Besta IRCCS Foundation, Via Celoria 11, 20133, Milan, Italy

    Alberto Raggi, Ambra Mara Giovannetti, Silvia Schiavolin & Matilde Leonardi

  2. Headache Unit, Department of Clinical Neuroscience, Neurological Institute C. Besta IRCCS Foundation, Milan, Italy

    Gennaro Bussone, Licia Grazzi, Susanna Usai, Marcella Curone, Paola Di Fiore & Domenico D’Amico

Authors
  1. Alberto Raggi
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  2. Ambra Mara Giovannetti
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  3. Silvia Schiavolin
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  4. Matilde Leonardi
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  5. Gennaro Bussone
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  6. Licia Grazzi
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  7. Susanna Usai
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  8. Marcella Curone
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  9. Paola Di Fiore
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  10. Domenico D’Amico
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Corresponding author

Correspondence to Alberto Raggi.

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Raggi, A., Giovannetti, A.M., Schiavolin, S. et al. Validating the Migraine-Specific Quality of Life Questionnaire v2.1 (MSQ) in Italian inpatients with chronic migraine with a history of medication overuse. Qual Life Res 23, 1273–1277 (2014). https://doi.org/10.1007/s11136-013-0556-9

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  • DOI: https://doi.org/10.1007/s11136-013-0556-9

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