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The psychosocial correlates of quality of life in the dialysis population: a systematic review and meta-regression analysis

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Abstract

Purpose

The psychosocial correlates of quality-of-life (QoL) research in end-stage renal disease (ESRD) are important in identifying risk and protective factors that may account for the QoL variability. Thus, the present study provides a meta-analysis of these research results.

Methods

Published studies reporting associations between any psychosocial factors and QoL were retrieved from Medline, Embase, and PsycINFO. Mean effect sizes were calculated for the associations across psychosocial constructs (affect, stress, cognitive appraisal, social support, personality attributes, and coping process). Multiple hierarchical meta-regressions were applied to moderator analyses.

Results

Eighty-one studies covering a combined sample of 13,240 participants were identified resulting in 377 effect sizes of the association between psychosocial factors and QoL. The overall effect size of the association was medium (0.38). Stress, affect, and cognitive appraisal had the largest effect sizes. Location of study, dialysis type, gender, age and QoL domains measured (general well-being, subjective QoL, and health-related QoL) were significant substantive moderators for the associations.

Conclusions

The present study shows that there is a moderate association between psychosocial variables and QoL in patients with ESRD, consistent across different QoL domains. The psychosocial constructs that have the strongest association with QoL are stress, affect, and cognitive appraisal.

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Abbreviations

ESr:

Effect size

ESRD:

End-stage renal disease

QoL:

Quality of life

HRQoL:

Health-related quality of life

CAPD:

Continuous ambulatory peritoneal dialysis

PD:

Peritoneal dialysis

PRISMA:

Preferred reporting items for systematic reviews and meta-analyses

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Acknowledgments

We are grateful for the authors of the included studies who provided additional data for this meta-analysis and the extensive support from the Renal Unit, Liverpool Hospital in completing this study.

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Authors and Affiliations

  1. Consultation Liaison Psychiatry, Liverpool Hospital, Locked Bag 7103, Liverpool BC, NSW, 1871, Australia

    Ramony Chan

  2. The University of New South Wales, Sydney, Australia

    Ramony Chan, Robert Brooks, Zachary Steel, Jonathan Erlich & Michael Suranyi

  3. Renal Unit, Liverpool Hospital, Sydney, Australia

    Ramony Chan, Josephine Chow & Michael Suranyi

  4. Centre for Population Mental Health Research, Liverpool Hospital, Sydney, Australia

    Robert Brooks & Zachary Steel

  5. The University of Western Sydney, Sydney, Australia

    Tracy Heung

  6. Department of Nephrology, Prince of Wales Hospital, Sydney, Australia

    Jonathan Erlich

  7. The University of Sydney, Sydney, Australia

    Josephine Chow

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Correspondence to Ramony Chan.

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Chan, R., Brooks, R., Steel, Z. et al. The psychosocial correlates of quality of life in the dialysis population: a systematic review and meta-regression analysis. Qual Life Res 21, 563–580 (2012). https://doi.org/10.1007/s11136-011-9973-9

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