Quality of life in pregnancy and post-partum: a study in diabetic patients

Abstract

Purpose

We evaluated quality of life in pregnant women with diabetes followed up at Italian diabetes clinics.

Methods

A total of 245 pregnant women (30 type 1 diabetes mellitus (T1DM), 176 gestational diabetes (GDM) and 39 controls) were asked to fill in a questionnaire including the SF-36 Health Survey and the Center for Epidemiological Studies-Depression (CES-D) Scale in third trimester of pregnancy and after delivery. GDM and T1DM also completed two diabetes-specific questionnaires (Diabetes-related stress and Diabetes health distress). Quality of life scores were compared between the groups with the Mann–Whitney U-test, mean changes in scores (after delivery to 3rd trimester) were compared between groups by ANCOVA.

Results

Regarding the SF-36 scores in the third trimester of pregnancy, T1DM and GDM women had a better Standardised Physical Component score than controls (P < 0.0001, P = 0.009, respectively). GDM and T1DM pregnant women scored significantly lower for general health perception than controls (P = 0.009 and P = 0.001, respectively). T1DM patients had lower Standardised Mental Component scores than controls (P = 0.03). Compared with the third trimester of pregnancy, the severity of depressive symptoms increased significantly after delivery in both diabetic groups, but not in controls (P < 0.0001). Scores improved in all SF-36 areas in healthy and GDM women, while they all became worse in the T1DM group.

Conclusions

Pregnancy is associated with a perception of poor general health in women with both T1DM and GDM. After delivery, significantly worse depressive symptoms were documented in both groups, while a generally worse physical and psychological well-being was only identified in women with T1DM. These findings have important implications for pregnancy follow-up.

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Affiliations

Authors

Corresponding author

Correspondence to A. Lapolla.

Additional information

On the behalf of QLISG. The details of QLISG is given in Appendix.

Appendix

Appendix

QLISG (Quality of Life Italian Study Group)

  • Di Benedetto A, DPT Medicina Interna Università di Messina,

  • Di Cianni G, DPT Endocrinologia e Malattie del Metabolismo,Università di Pisa,

  • Dolci MA,UO Diabetolologia, Ospedale Massa,

  • Franzetti I, UO Diabetologia, Ospedale Varese,

  • Galluzzo A, DPT Endocrinologia, Università di Palermo,

  • Napoli A, UO Malattie Metaboliche, Università La Sapienza Roma,

  • Salietti G, UO Diabetologia, Ospedale Omegna,

  • Santini C, UO Diabetologia, Cesena,

  • Torlone E, DIMISEM, Università di Perugia,

  • Tortul C, UO Diabetolologia, ASL Isontina,

  • Vitacolonna E, UO Diabetologia, Università di Chieti.

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Dalfrà, M.G., Nicolucci, A., Bisson, T. et al. Quality of life in pregnancy and post-partum: a study in diabetic patients. Qual Life Res 21, 291–298 (2012). https://doi.org/10.1007/s11136-011-9940-5

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Keywords

  • Quality of life
  • Pregnancy
  • Gestational diabetes
  • Type 1 diabetes mellitus
  • Insulin therapy