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Quality of life in Parkinson’s disease patients: validation of the Short-Form Eight-item Parkinson’s Disease Questionnaire (PDQ-8) in Taiwan

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Abstract

Purpose

This study sought to evaluate the Chinese version of the eight-item Parkinson’s Disease Questionnaire (PDQ-8), through standard psychometric techniques.

Methods

A cross-sectional study was conducted on 100 Parkinson’s disease patients attending a Movement Disorders Unit. Neurologists’ assessments were based on Hoehn and Yahr, Schwab and England and Unified Parkinson’s Disease Rating Scales. Patients’ self-evaluations included the Taiwanese Depression Questionnaire, the 39-item Parkinson’s Disease Questionnaire (PDQ-39) and PDQ-8, pain, and Pittsburgh Sleep Quality Index. Analyses for internal consistency, inter-rater reliability, and construct validity were performed.

Results

There was no evidence of floor or ceiling effects. The alpha coefficient was 0.81. Correlation of social support and bodily discomfort with the PDQ-8 was modest (0.46 and 0.36, respectively). PDQ-8 convergent validity with the PDQ-39 was very high (r = 0.96), and known-groups validity proved satisfactory.

Conclusions

The results of this study suggest the PDQ-8 is a valid and reliable disease-specific health-related quality-of-life instrument for Parkinson’s disease in Taiwan when used independently of the PDQ-39.

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Abbreviations

ADL:

Activities of daily living

AGFI:

Adjusted goodness-of-fit index

ANOVA:

Analysis of variance

CFI:

Comparative fit index

GFI:

Goodness-of-fit index

HRQoL:

Health-related quality of life

H & Y:

Hoehn and Yahr

PDQ-8:

Eight-item Parkinson’s Disease Questionnaire

PDQ-39:

Thirty-nine-item Parkinson’s Disease Questionnaire

PSQI:

Pittsburgh Sleep Quality Index

RMSEA:

Root-mean-square error of approximation

TDQ:

Taiwanese Depression Questionnaire

UPDRS:

Unified Parkinson’s Disease Rating Scale

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Acknowledgments

The authors are grateful to thank all the study participants for sharing their experiences.

Ethical approval

This study has been approved by the Institutional Review Board of Chung-Gung University.

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Correspondence to Tzu-Ting Huang.

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Huang, TT., Hsu, HY., Wang, BH. et al. Quality of life in Parkinson’s disease patients: validation of the Short-Form Eight-item Parkinson’s Disease Questionnaire (PDQ-8) in Taiwan. Qual Life Res 20, 499–505 (2011). https://doi.org/10.1007/s11136-010-9777-3

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  • DOI: https://doi.org/10.1007/s11136-010-9777-3

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