Skip to main content

Advertisement

SpringerLink
Log in

Validation of a Chinese version of the Medical Outcomes Study HIV Health Survey (MOS-HIV) among Chinese people living with HIV/AIDS in Hong Kong

  • Published:
Quality of Life Research Aims and scope Submit manuscript

Abstract

Objectives: To evaluate the Chinese version of the 35-item Medical Outcomes Study HIV Health Survey (MOS-HIV) in Chinese people living with HIV/AIDS (PLWHA). Methods: A cross-sectional survey of 242 ethnic Chinese PLWHA in Hong Kong was conducted. Results: Cronbach’s αs of the eight multi-item scales of the MOS-HIV ranged from 0.78 to 0.90. Item-total and inter-scale correlation coefficients were acceptable. Factor analysis of the MOS-HIV identified two factors (Mental Health Summary scores and Physical Health Summary scores, or MHS and PHS), accounting for 63% total variance. The PHS and MHS correlated significantly with the WHOQOL-BREF(HK) and the three sub-scales of Profile of Mood States used in this study. Both PHS and MHS were significantly associated with self-perceived change in health status. PHS but not MHS was associated with Karnofsky Performance Status scores. PHS was also associated with disease stage. The MOS-HIV however, did not distinguish between groups of different CD4 cell counts. It is likely that the quality of life of these PLWHA of different disease stages was good in general. Conclusions: There is a large demand for evaluating treatments and services programs offered to PLWHA in China. The validated Chinese MOS-HIV would facilitate such research activities.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. J Baigis DM Korniewicz G Chase A Butz D Jacobson AW Wu (2002) ArticleTitleEffectiveness of a home-based exercise intervention for HIV-infected adults: A randomized trial J Assoc Nurses AIDS Care 13 33–45 Occurrence Handle11936063 Occurrence Handle10.1016/S1055-3290(06)60199-4

    Article  PubMed  Google Scholar 

  2. SA Bozzette DE Kanouse S Berry N Duan (1995) ArticleTitleHealth status and function with zidovudine or zalcitabine as initial therapy for AIDS. A randomized controlled trial. Roche 3300/ACTG 114 Study Group JAMA 273 295–301 Occurrence Handle7815656 Occurrence Handle1:STN:280:ByqC3MrisVw%3D Occurrence Handle10.1001/jama.273.4.295

    Article  PubMed  CAS  Google Scholar 

  3. R Murri M Fantoni C Del Borgo et al. (2003) ArticleTitleDeterminants of health-related quality of life in HIV-infected patients AIDS Care 15 581–590 Occurrence Handle14509872 Occurrence Handle1:STN:280:DC%2BD3svkvFShtA%3D%3D Occurrence Handle10.1080/0954012031000134818

    Article  PubMed  CAS  Google Scholar 

  4. DF Cella NL McCain AH Peterman F Mo D Wolen (1996) ArticleTitleDevelopment and validation of the Functional Assessment of Human Immunodeficiency Virus Infection (FAHI) quality of life instrument Qual Life Res 5 450–463 Occurrence Handle8840825 Occurrence Handle1:STN:280:BymH3sfktVI%3D Occurrence Handle10.1007/BF00449920

    Article  PubMed  CAS  Google Scholar 

  5. WC Holmes JA Shea (1998) ArticleTitleA new HIV/AIDS-targeted quality of life (HAT-QoL) instrument: development, reliability, and validity Med Care 36 138–154 Occurrence Handle9475469 Occurrence Handle1:STN:280:DyaK1c7jtlKitA%3D%3D Occurrence Handle10.1097/00005650-199802000-00004

    Article  PubMed  CAS  Google Scholar 

  6. AW Wu HR Rubin WC Mathews et al. (1991) ArticleTitleA health status questionnaire using 30 items from the Medical Outcomes Study: Preliminary validation in persons with early HIV infection Med Care 29 786–798 Occurrence Handle1875745 Occurrence Handle1:STN:280:By6A2c3is1I%3D

    PubMed  CAS  Google Scholar 

  7. AW Wu RD Hays S Kelly F Malitz SA Bozzette (1997) ArticleTitleApplications of the Medical Outcomes Study health-related quality of life measures in HIV/AIDS Qual Life Res 6 531–534 Occurrence Handle9330553 Occurrence Handle1:STN:280:ByiH2s7mtFY%3D Occurrence Handle10.1023/A:1018460132567

    Article  PubMed  CAS  Google Scholar 

  8. JA Scott-Lennox AW Wu G Boyer JE Ware SuffixJr. (1999) ArticleTitleReliability and validity of French, German, Italian, Dutch, and UK English Translations of the Medical Outcomes Study HIV Health Survey Med Care 37 908–925 Occurrence Handle10493469 Occurrence Handle1:STN:280:DyaK1MvitFaisA%3D%3D Occurrence Handle10.1097/00005650-199909000-00007

    Article  PubMed  CAS  Google Scholar 

  9. X Badia D Podzamczer C Lopez-Lavid M Garcia (1999) ArticleTitleEvidence-based medicine and the validation of quality-of-life questionnaires: The Spanish version of the MOS-HIV questionnaire for the evaluation of the quality of life in patients infected by HIV. [Spanish] Enferm Infecc Microbiol Clin 17 IssueIDSuppl 2 103–113 Occurrence Handle10605195

    PubMed  Google Scholar 

  10. M Ichikawa C Natpratan (2004) ArticleTitleQuality of life among people living with HIV/AIDS in northern Thailand: MOS-HIV Health Survey Qual Life Res 13 601–610 Occurrence Handle15130024 Occurrence Handle10.1023/B:QURE.0000021319.73865.5a

    Article  PubMed  Google Scholar 

  11. R Murri A Ammassari M Fantoni et al. (1997) ArticleTitleDisease-related factors associated with health-related quality of life in people with nonadvanced HIV disease assessed using an Italian version of the MOS-HIV Health Survey J Acquir Immune Defic Syndr Hum Retrovirol 16 350–356 Occurrence Handle9420313 Occurrence Handle1:STN:280:DyaK1c%2FotVGjsA%3D%3D

    PubMed  CAS  Google Scholar 

  12. A Burgess M Dayer J Catalan D Hawkins B Gazzard (1993) ArticleTitleThe reliability and validity of two HIV-specific health-related quality of life measures: A preliminary analysis AIDS 7 1001–1008 Occurrence Handle8357546 Occurrence Handle1:STN:280:ByyA28zisVQ%3D

    PubMed  CAS  Google Scholar 

  13. MD Carretero AP Burgess P Soler M Soler J Catalan (1996) ArticleTitleReliability and validity of an HIV-specific health-related quality-of-life measure for use with injecting drug users AIDS 10 1699–1705 Occurrence Handle8970691 Occurrence Handle1:STN:280:ByiC38rmtF0%3D

    PubMed  CAS  Google Scholar 

  14. AE Copfer NM Ampel TE Hughes et al. (1996) ArticleTitleThe use of two measures of health-related quality of life in HIV-infected individuals: A cross-sectional comparison Qual Life Res 5 281–286 Occurrence Handle8998497 Occurrence Handle1:STN:280:ByiC3cvntFA%3D Occurrence Handle10.1007/BF00434750

    Article  PubMed  CAS  Google Scholar 

  15. T Delate SJ Coons (2001) ArticleTitleThe use of 2 health-related quality-of-life measures in a sample of persons infected with human immunodeficiency virus Clin Infect Dis 32 E47–E52 Occurrence Handle11170970 Occurrence Handle1:STN:280:DC%2BD38%2Fgs12rtQ%3D%3D Occurrence Handle10.1086/318492

    Article  PubMed  CAS  Google Scholar 

  16. WC Holmes JA Shea (1999) ArticleTitleTwo approaches to measuring quality of life in the HIV/AIDS population: HAT-QoL and MOS-HIV Qual Life Res 8 515–527 Occurrence Handle10548867 Occurrence Handle1:STN:280:DC%2BD3c%2Fhs1GrsQ%3D%3D Occurrence Handle10.1023/A:1008931006866

    Article  PubMed  CAS  Google Scholar 

  17. TE Hughes RM Kaplan SJ Coons JR Draugalis JA Johnson TL Patterson (1997) ArticleTitleConstruct validities of the quality of well-being scale and the MOS-HIV-34 Health Survey for HIV-infected patients Med Decis Making 17 439–446 Occurrence Handle9343802 Occurrence Handle1:STN:280:DyaK1c%2FgtlOjsA%3D%3D

    PubMed  CAS  Google Scholar 

  18. DA Revicki AW Wu MI Murray (1995) ArticleTitleChange in clinical status, health status, and health utility outcomes in HIV-infected patients Med Care 33 173–182

    Google Scholar 

  19. AW Wu DA Revicki D Jacobson FE Malitz (1997) ArticleTitleEvidence for reliability, validity, and usefulness of the Medical Outcomes Study HIV Health Survey (MOS HIV) Qual Life Res 6 481–493 Occurrence Handle9330549 Occurrence Handle1:STN:280:ByiH2s7mtVw%3D Occurrence Handle10.1023/A:1018451930750

    Article  PubMed  CAS  Google Scholar 

  20. Advisory Council on AIDS. Cumulative HIV/AIDS statistics in Hong Kong (updated 31 March 2000). ACA Newsfile 2000; 7: 27

    Google Scholar 

  21. JTF Lau HY Tsui CK Li RW Chung MW Chan A Molassiotis (2003) ArticleTitleNeeds assessment and social environment of people living with HIV/AIDS in Hong Kong AIDS Care 15 699–706 Occurrence Handle12959821 Occurrence Handle1:STN:280:DC%2BD3svitVWiuw%3D%3D Occurrence Handle10.1080/09540120310001595186

    Article  PubMed  CAS  Google Scholar 

  22. DA Revicki S Sorensen AW Wu (1998) ArticleTitleReliability and validity of physical and mental health summary scores from the Medical Outcomes Study HIV Health Survey Med Care 36 126–137 Occurrence Handle9475468 Occurrence Handle1:STN:280:DyaK1c7jtlKitw%3D%3D Occurrence Handle10.1097/00005650-199802000-00003

    Article  PubMed  CAS  Google Scholar 

  23. V Mor L Laliberte JN Morris M Wiemann (1984) ArticleTitleThe Karnofsky performance status scale: an examination of its reliability and validity in a research setting Cancer 53 2002–2007 Occurrence Handle6704925 Occurrence Handle1:STN:280:BiuC2MnhsFU%3D Occurrence Handle10.1002/1097-0142(19840501)53:9<2002::AID-CNCR2820530933>3.0.CO;2-W

    Article  PubMed  CAS  Google Scholar 

  24. Centers for Disease Control and Prevention. 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. Morb Mortal Wkly Rep Recomm Rep 1992; 41(RR-17): 1–19

    Google Scholar 

  25. Scientific Committee on AIDS. Classification system for HIV infection and surveillance case definition for AIDS in adolescents and adults in Hong Kong. Hong Kong: Scientific Committee on AIDS, Advisory Council on AIDS. July 1995

  26. InstitutionalAuthorNameThe WHOQOL Group (1998) ArticleTitleDevelopment of the World Health Organization WHOQOL-BREF quality of life assessment Psychol Med 28 551–558 Occurrence Handle10.1017/S0033291798006667

    Article  Google Scholar 

  27. Hong Kong Project Team on the Development of the Hong Kong Chinese version WHOQOL. Hong Kong Chinese version World Health Organisation quality of life measure – abbreviated version WHOQOL-BREF (HK). Hong Kong Hospital Authority. December 1997

  28. DM McNair M Lorr LF Droppelman (1971) Manual for the Profile of Mood States Educational and Industrial Testing Service San Diego

    Google Scholar 

  29. A Molassiotis E Holroyd R Taylor-Piliae (1999) ArticleTitlePsychometric evaluation of the Chinese translation of the Profile of Mood States Hong Kong Nursing J 35 IssueID2 7–13

    Google Scholar 

  30. Sharma S. Applied Multivariate Techniques. John Wiley and Sons Inc., 1996

  31. X Badia D Podzamczer M Garcia CC Lopez-Lavid E Consiglio (1999) ArticleTitleThe Spanish MOS-HIV and MQOL-HIV Validation Group. A randomized study comparing instruments for measuring health-related quality of life in HIV-infected patients AIDS 13 1727–1735 Occurrence Handle10509575 Occurrence Handle1:STN:280:DyaK1Mvjslaktg%3D%3D Occurrence Handle10.1097/00002030-199909100-00017

    Article  PubMed  CAS  Google Scholar 

  32. WH Kuang J Li YG Ma J Liao (2005) ArticleTitleSurvey on psychologic status and quality of life for HIV infected people or AIDS patients. [Chinese] J Sichuan University, Med Sci Edn 36 IssueID1 97–100

    Google Scholar 

  33. The UN Theme Group on HIV/AIDS in China. HIV/AIDS: China’s titanic Peril – 2001 Update of the AIDS Situation and needs Assessment Report. June 2002

  34. Y Yang KL Zhang (2004) ArticleTitleHIV/AIDS-related discrimination in Shanxi rural areas of China Biomed Environ Sci 17 IssueID4 410–417 Occurrence Handle15745245 Occurrence Handle10.1159/000077341

    Article  PubMed  Google Scholar 

  35. People’s Daily Online. China announces list of 51 AIDS pilot zones (6 April 2004). Assessed 22 July 2004. Available from: http://www.english.peopledaily.com.cn/200404/06/eng20040406_139553.shtml

  36. NI Paton CAT Chapman SP Chan et al. (2002) ArticleTitleValidation of the Medical Outcomes Study HIV Health Survey as a measure of quality of life in HIV-infected patients in Singapore Int J STD AIDS 13 456–461 Occurrence Handle12171664 Occurrence Handle10.1258/09564620260079608

    Article  PubMed  Google Scholar 

  37. Shahriar J, Delate T, Hays RD, Coons J. Commentary on using the SF-36 or MOS-HIV in studies of persons with HIV disease. Health and Quality of Life Outcomes 2003, 1:25 (9 July 2003). Available at http://www.hqlo.com/content/1/1/25

  38. DM Osowiecki RA Cohen KM Morrow et al. (2000) ArticleTitleNeurocognitive and psychological contributions to quality of life in HIV-1-infected women AIDS 14 1327–1332 Occurrence Handle10930146 Occurrence Handle1:STN:280:DC%2BD3M%2FlsV2ruw%3D%3D Occurrence Handle10.1097/00002030-200007070-00004

    Article  PubMed  CAS  Google Scholar 

  39. Ho CF, Wong HY, Wong KH, et al. Determinants of quality of life in HIV-infected Chinese patients. Poster Presentation at the XII International Congress on AIDS in Asia and the Pacific. Kobe. 1–5 July 2005. [Poster no. SuPB0053]

Download references

Author information

Authors and Affiliations

  1. Centre for Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, The Chinese University of Hong Kong, 5/F., School of Public Health Prince of Wales Hospital, Shatin, NT, Hong Kong

    Joseph T. F. Lau & Hi Yi Tsui

  2. Special Medical Service, Department of Medicine, Queen Elizabeth Hospital, Kowloon, Hong Kong

    Li C. K. Patrick & Chung W. Y. Rita

  3. School of Nursing, University of Manchester, Manchester, UK

    Alexander Molassiotis

Authors
  1. Joseph T. F. Lau
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hi Yi Tsui
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Li C. K. Patrick
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Chung W. Y. Rita
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Alexander Molassiotis
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Joseph T. F. Lau.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lau, J.T.F., Tsui, H.Y., Patrick, L.C.K. et al. Validation of a Chinese version of the Medical Outcomes Study HIV Health Survey (MOS-HIV) among Chinese people living with HIV/AIDS in Hong Kong. Qual Life Res 15, 1079–1089 (2006). https://doi.org/10.1007/s11136-005-5914-9

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11136-005-5914-9

Keywords

Search

Navigation