Prevention Science

, Volume 15, Issue 5, pp 767–776 | Cite as

Cross-national Comparison of Prenatal Methamphetamine Exposure on Infant and Early Child Physical Growth: A Natural Experiment

  • Beau AbarEmail author
  • Linda L. LaGasse
  • Trecia Wouldes
  • Chris Derauf
  • Elana Newman
  • Rizwan Shah
  • Lynne M. Smith
  • Amelia M. Arria
  • Marilyn A. Huestis
  • Sheri DellaGrotta
  • Lynne M. Dansereau
  • Tara Wilcox
  • Charles R. Neal
  • Barry M. Lester


The current study seeks to compare the effects of prenatal methamphetamine exposure (PME) on infant and child physical growth between the USA and New Zealand (NZ). This cross-national comparison provides a unique opportunity to examine the potential impact of services provided to drug using mothers on child health. The longitudinal Infant Development, Environment and Lifestyle study of PME from birth to 36 months was conducted in the USA and NZ. The US cohort included 204 children with PME and 212 non-PME matched comparisons (NPME); the NZ cohort included 108 children with PME and 115 NPME matched comparisons. Latent growth curve models were used to examine effects of PME, country of origin, and the country × PME interaction on growth in length/height and weight. In regard to length/height, PME and country of origin were associated with initial length and growth over time. There was also a significant interaction effect, such that children with PME in the USA were shorter at birth than children with PME in NZ after controlling for other prenatal exposures, infant set, socioeconomic status, and maternal height. In regard to weight, there was only an effect of country of origin. Effects of PME on infant and child growth were shown to differ across countries, with exposed children in NZ faring better than exposed children in the USA. Implications for prevention programs and public policy are discussed.


Prenatal methamphetamine exposure Length/height Weight Cross-national research 


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Copyright information

© Society for Prevention Research 2013

Authors and Affiliations

  • Beau Abar
    • 1
    Email author
  • Linda L. LaGasse
    • 1
  • Trecia Wouldes
    • 2
  • Chris Derauf
    • 3
  • Elana Newman
    • 4
  • Rizwan Shah
    • 5
  • Lynne M. Smith
    • 6
  • Amelia M. Arria
    • 7
  • Marilyn A. Huestis
    • 8
  • Sheri DellaGrotta
    • 1
  • Lynne M. Dansereau
    • 1
  • Tara Wilcox
    • 1
  • Charles R. Neal
    • 3
  • Barry M. Lester
    • 1
  1. 1.Brown Center for the Study of Children at RiskAlpert Medical School, Women and Infants Hospital of RIProvidenceUSA
  2. 2.Department of Psychological MedicineThe University of AucklandAucklandNew Zealand
  3. 3.John A. Burns School of Medicine, Department of PediatricsUniversity of HawaiiPearl CityUSA
  4. 4.Department of PsychologyThe University of TulsaTulsaUSA
  5. 5.Blank Hospital Regional Child Protection CenterIowa HealthDes MoinesUSA
  6. 6.Department of PediatricsLABioMed Institute at Harbor-UCLA Medical CenterLos AngelesUSA
  7. 7.Family Science Department–Center on Young Adult Health and DevelopmentUniversity of Maryland School of Public HealthCollege ParkUSA
  8. 8.Intramural Research ProgramNational Institute on Drug AbuseBethesdaUSA

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