Skip to main content
Log in

A rare case of paraganglioma of the sella with bone metastases

  • Case Report
  • Published:
Pituitary Aims and scope Submit manuscript

Abstract

Sellar paragangliomas are very rare lesions with only 11 previous cases described in the literature. We present a further case of sellar paraganglioma. The patient is a 17-year-old man who developed headache, visual blurring, and diplopia. MRI showed a sellar lesion. Trans-nasal trans-sphenoid biopsy showed features of paraganglioma. He was treated by Stereotactic radiotherapy. Four months after treatment he developed bone metastases which was palliated by radiation, zoledronic acid, and chemotherapy. This is the first case of sellar paraganglioma showing metastases to bone.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

References

  1. Scheithauer BW, Parameswaran A, Burdick B (1996) Intrasellar paraganglioma report of a case in a sib ship of von Hippel-Lindau disease. Neurosurgery 38:395–399 Medline. doi:10.1097/00006123-199602000-00034

    Article  PubMed  CAS  Google Scholar 

  2. Hertel F, Bettag M, Morsdorf M, Feiden W (2003) Paragangliomas of the parasellar region. Neurosurg Rev 26:210–214 Medline

    PubMed  CAS  Google Scholar 

  3. Wasserman PG, Savargaonkar P (2001) Paragangliomas: classification, pathology and differential diagnosis. Otolaryngol Clin North Am 34:845–862 Medline. doi:10.1016/S0030-6665(05)70351-0

    Article  PubMed  CAS  Google Scholar 

  4. Salame K, Ouaknine GE, Yossipov J, Rochkind S (2001) Paraganglioma of the pituitary fossa: diagnosis and management. J Neurooncol 54:49–52 Medline. doi:10.1023/A:1012535230135

    Article  PubMed  CAS  Google Scholar 

  5. Boari N, Losa M, Mortini P, Snider S, Terreni MR, Giovanelli M (2006) Intrasellar paraganglioma: a case report and review of the literature. Acta Neurochir (Wien) 148:1311–1314 Medline. doi:10.1007/s00701-006-0895-1

    Article  CAS  Google Scholar 

  6. Zorlu F, Selek U, Ulger S, Donmez T, Erden E (2006) Paraganglioma in sella. J Neurooncol 73:265–267 Medline. doi:10.1007/s11060-004-5673-4

    Article  Google Scholar 

  7. Mokry M, Kleinert R, Clarici G, Obermayer-Pietsch B (1998) Primary paraganglioma simulating pituitary macroadenoma: a case report and review of the literature. Neuroradiology 40:233–237 Medline. doi:10.1007/s002340050573

    Article  PubMed  CAS  Google Scholar 

  8. Sambaziotis D, Kontogeorgos G, Kovacs K, Horvath E, Levedis A (1999) Intrasellar paraganglioma presenting as nonfunctioning pituitary adenoma. Arch Pathol Lab Med 123:429–432 Medline

    PubMed  CAS  Google Scholar 

  9. Del Basso De Caro ML, Siciliano A, Cappabianca P, Alfieri A, de Divitiis E (1996) Intrasellar paraganglioma with suprasellar extension: case report. Tumori 84:408–411 Medline

    Google Scholar 

  10. Steel TR, Dailey AT, Born D, Berger MS, Mayberg MR (1993) Paragangliomas of the sellar region: report of two cases. Neurosurgery 32:844–847 Medline. doi:10.1097/00006123-199305000-00021

    Article  PubMed  CAS  Google Scholar 

  11. Flint EW, Claassen D, Pang D, Hirsch WL (1993) Intrasellar and suprasellar paraganglioma: CT and MR finding. AJNR Am J Neuroradiol 14:1191–1193 Medline

    PubMed  CAS  Google Scholar 

  12. Bilbao JM, Horvath E, Kovacs K, Singer W, Hudson AR (1978) Intrasellar paraganglioma associated with hypopituitarism. Arch Pathol Lab Med 102:95–98 Medline

    PubMed  CAS  Google Scholar 

  13. Myssiorek D (2001) Head and neck paragangliomas: an overview. Otolaryngol Clin North Am 34:829–836 Medline. doi:10.1016/S0030-6665(05)70349-2

    Article  PubMed  CAS  Google Scholar 

  14. Gulya AJ (1993) The glomus tumor and its biology. Laryngoscope 103:7–15 Medline. doi:10.1288/00005537-199307000-00009

    Article  PubMed  CAS  Google Scholar 

  15. Scheithauer BW, Parameswaran A, Burdick B, Marrinan M (2001) Head and neck paragangliomas: physiology and biochemistry. Otolaryngol Clin North Am 34:837–844 Medline. doi:10.1016/S0030-6665(05)70350-9

    Article  Google Scholar 

  16. Voulgaris SG, Partheni M, Tzortzidis F et al (2006) Suprasellar and intrasellar paragangliomas. Clin Neuropathol 25:221–226 Medline

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to K. P. Haresh.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Haresh, K.P., Prabhakar, R., Anand Rajan, K.D. et al. A rare case of paraganglioma of the sella with bone metastases. Pituitary 12, 276–279 (2009). https://doi.org/10.1007/s11102-008-0099-1

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11102-008-0099-1

Keywords

Navigation