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Pituitary apoplexy during treatment of cystic macroprolactinomas with cabergoline

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Abstract

Pituitary apoplexy is a rare and life-threatening clinical condition caused by hemorrhage and/or infarction of the pituitary gland or adenoma. Although pituitary apoplexy is usually spontaneous, it has been associated with numerous precipitating factors, such as bromocriptine use. However, reports of pituitary apoplexy during cabergoline therapy are scarce. We report three patients with cystic macroprolactinomas who developed pituitary apoplexy during cabergoline treatment.

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Abbreviations

MRI:

Magnetic resonance imaging

CT:

Computed tomography

PRL:

Prolactin

DA:

Dopamine agonist

RNA:

Ribonucleic acid

cAMP:

Cyclic AMP

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Authors and Affiliations

  1. Division of Endocrinology, Clementino Fraga Filho University Hospital/Federal University of Rio de Janeiro, Rua Professor Rodolpho Paulo Rocco, no. 255, Cidade Universitária - Ilha do Fundão, Rio de Janeiro, RJ, Brazil

    Giovanna Aparecida Balarini Lima, Evelyn de Oliveira Machado, Cintia Marques dos Santos Silva & Mônica Roberto Gadelha

  2. Division of Neurosurgery, Santa Casa de Misericórdia do Rio de Janeiro, Rio de Janeiro, RJ, 21941-913, Brazil

    Paulo Niemeyer Filho

  3. Rua Nascimento Silva 555, apt 101, Rio de Janeiro, RJ, 22421-020, Brazil

    Mônica Roberto Gadelha

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  1. Giovanna Aparecida Balarini Lima
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  2. Evelyn de Oliveira Machado
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  3. Cintia Marques dos Santos Silva
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  5. Mônica Roberto Gadelha
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Correspondence to Mônica Roberto Gadelha.

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Balarini Lima, G.A., Machado, E.O., dos Santos Silva, C.M. et al. Pituitary apoplexy during treatment of cystic macroprolactinomas with cabergoline. Pituitary 11, 287–292 (2008). https://doi.org/10.1007/s11102-007-0046-6

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