Phytochemistry Reviews

, Volume 17, Issue 4, pp 903–921 | Cite as

Carvacrol and its derivatives as antibacterial agents

  • Lisa Marinelli
  • Antonio Di Stefano
  • Ivana Cacciatore


In recent years, essential oils constituents have attracted interest as alternative approach in the traditional medicine for their therapeutics properties. In this field, carvacrol, since it showed strong antimicrobial activity against a wide range of Gram-positive and -negative bacteria, has emerged as active molecule for therapeutic purpose. This review focuses on the antimicrobial properties of carvacrol and highlights the advantageous impact of the medicinal chemistry and technological-based approaches employed to improve its therapeutic profile.

Graphical Abstract


Antimicrobials Carvacrol Carvacrol derivatives Essential oils 


Compliance with ethical standards

Conflict of interest

The authors declare not conflict of interest.


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Copyright information

© Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  • Lisa Marinelli
    • 1
  • Antonio Di Stefano
    • 1
  • Ivana Cacciatore
    • 1
  1. 1.Department of PharmacyUniversity “G. d’Annunzio”ChietiItaly

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