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Phytochemistry Reviews

, Volume 17, Issue 3, pp 471–489 | Cite as

Chemistry and medicinal uses of the subfamily Barnadesioideae (Asteraceae)

  • Gari V. Ccana-Ccapatinta
  • Marcelo Monge
  • Paola L. Ferreira
  • Fernando B. Da Costa
Article
  • 335 Downloads

Abstract

The subfamily Barnadesioideae (Asteraceae) constitutes a group of spiny plants that are entirely restricted to South America and currently encompasses 92 species distributed in nine genera. Barnadesioideae is particularly interesting because this subfamily constitutes the sister group of all other Asteraceae, and provides insights into the early evolution of Asteraceae. The present work summarizes the current knowledge of the chemistry and medicinal uses of Barnadesioideae. The up-to-date phytochemical profile of Barnadesioideae is composed of phenolic compounds, flavonoids, and triterpenoids, representing 39 different compounds described in 45 species of the subfamily. The presumable absence of sesquiterpene lactones—the typical Asteraceae taxonomical markers—in members of Barnadesioideae is also discussed. A few members of the genera Barnadesia, Dasyphyllum, and more frequently, Chuquiraga, are reported in the traditional medicine of Argentina, Brazil, Bolivia, Chile, Colombia, Ecuador, and Peru, where they are known for their antitussive, expectorant, anti-inflammatory, and many other properties. Chuquiraga jussieui, Chuquiraga spinosa, and Chuquiraga weberbaueri are species frequently sold in medicinal plant markets of Ecuador and Peru, where they are commonly recommended for the relief of genitourinary and reproductive disorders in women and men. Some phytopharmaceuticals containing C. spinosa are also marketed in Europe and North America. Further phytochemical studies on the members of Barnadesioideae would be of great interest for the chemotaxonomy of the family Asteraceae. Moreover, profiling the phytochemical composition of those medically important Barnadesioideae would support their uses in traditional medicine.

Keywords

Barnadesioideae Flavonoids Triterpenoids Traditional medicine 

Notes

Acknowledgements

The authors acknowledge the Brazilian research funding agencies Foundation for the Coordination and Improvement of Higher Level or Education Personnel (CAPES), National Council for Scientific and Technological Development (CNPq), and São Paulo Research Foundation (FAPESP, Grants #2014/16850-6 and #2014/26866-7) for fellowship and funding. Mr. G.F. Padilla-González (FCFRP-USP) is acknowledged for his comments on the manuscript. We thank Dr. G. Shimizu (Inst. Biology, UNICAMP) and Dr. G. Heiden (EMBRAPA Temperate Agriculture) for providing pictures of Barnadesioideae. We also acknowledge Prof. Dr. M. Groppo Jr. (Dept. Biology, FFCLRP-USP) and Prof. Dr. J. Semir (Inst. Biology, UNICAMP) for their valuable support and discussions.

Supplementary material

11101_2017_9544_MOESM1_ESM.docx (258 kb)
Supplementary material 1 (DOCX 257 kb)

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© Springer Science+Business Media B.V., part of Springer Nature 2017

Authors and Affiliations

  1. 1.AsterBioChem Research Team, Laboratory of Pharmacognosy, School of Pharmaceutical Sciences of Ribeirão Preto (FCFRP)University of São Paulo (USP)Ribeirão PrêtoBrazil
  2. 2.Graduate Program of Plant Biology, Institute of BiologyUniversity of Campinas (UNICAMP)CampinasBrazil
  3. 3.Laboratory of Plant Systematics, Department of Biology, Faculty of Philosophy, Sciences and Letters at Ribeirão Preto (FFCLRP)USPRibeirão PrêtoBrazil

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