Abstract
Background Prescription opioid use and related harms have dramatically increased in many countries. Objective To investigate pharmacists’ preparedness and confidence to intervene when concerned about supplying prescription opioids and strategies used when concerned about supplying these opioids. Setting Online survey among a representative sample of Australian community pharmacists. Method Pharmacists completed an online survey about their concerns, comfort and strategies used when supplying prescription opioids. Correlates of comfort to intervene and active intervention strategies were explored using multivariable ordered logistic regression and adjusted odd ratios (aOR) and 95% confidence intervals were reported. Main outcome measures Comfort to intervene when concerned about supplying prescription opioids and pharmacists’ discussing these concerns with the patient, and the prescriber. Results Most pharmacists were concerned about supplying prescription opioids to patients in the past week. Being female [adjusted odds ratio (aOR) 0.63; 95% confidence interval (CI) 0.47–0.85] was associated with reduced comfort, while practicing within a large chain pharmacy (aOR 1.52, 95% CI 1.08–2.15) was associated with greater comfort to intervene when concerned about prescription opioid supply. Pharmacists practicing in rural areas were significantly less likely than those in capital cities to discuss concerns with patients (aOR 0.66, 95% CI 0.45–0.97). Post-graduate education about substance use disorders was associated with increased likelihood of discussing concerns with patients (aOR 1.54, 95% CI 1.12–2.13). Pharmacists that indicated greater comfort in intervening when concerned about prescription opioids were more likely to discuss concerns with both patients and prescribers. Females were significantly more likely to discuss concerns with prescribers (aOR 1.67, 95% CI 1.22–2.29), whereas years of practice reduced the odds of discussing concerns with prescribers (aOR 0.98, 95% CI 0.97–0.99). Conclusion Considering specific factors such as gender and years of practice to help target pharmacist training may lead to increased comfort in discussing concerns related to prescription opioids, which in turn may improve communication with prescribers and patients.
Similar content being viewed by others
References
Degenhardt L, Grebely J, Stone J, Hickman M, Vickerman P, Marshall BDL, et al. Global patterns of opioid use and dependence: harms to populations, interventions, and future action. Lancet. 2019;394(10208):1560–79.
Cochran G, Field C, Lawson K. Pharmacists who screen and discuss opioid misuse with patients: future directions for research and practice. J Pharm Pract. 2015;28(4):404–12.
Blanch B, Pearson SA, Haber PS. An overview of the patterns of prescription opioid use, costs and related harms in Australia. Br J Clin Pharmacol. 2014;78(5):1159–66.
Larance B, Degenhardt L, Peacock A, Gisev N, Mattick R, Colledge S, et al. Pharmaceutical opioid use and harm in Australia: the need for proactive and preventative responses. Drug Alcohol Rev. 2017;37:S203–5.
Nielsen S, Bruno R, Lintzeris N, Fischer J, Carruthers S, Stoove M. Pharmaceutical opioid analgesic and heroin dependence: How do treatment-seeking clients differ in Australia? Drug Alcohol Rev. 2011;30(3):291–9.
Roxburgh A, Hall WD, Dobbins T, Gisev N, Burns L, Pearson S, et al. Trends in heroin and pharmaceutical opioid overdose deaths in Australia. Drug Alcohol Depend. 2017;179:291–8.
Campbell G, Bruno R, Lintzeris N, Cohen M, Nielsen S, Hall W, et al. Defining problematic pharmaceutical opioid use among people prescribed opioids for chronic noncancer pain: Do different measures identify the same patients? Pain. 2016;157(7):1489–98.
Campbell G, Nielsen S, Larance B, Bruno R, Mattick R, Hall W, et al. Pharmaceutical opioid use and dependence among people living with chronic pain: associations observed within the pain and opioids in treatment (POINT) cohort. Pain Med. 2015;16:1745–58.
Green TC, Dauria EF, Bratberg J, Davis CS, Walley AY. Orienting patients to greater opioid safety: models of community pharmacy-based naloxone. Harm Reduct J. 2015;12(1):25.
Australian Institute of Health Welfare. Alcohol, tobacco and other drugs in Australia. Canberra: AIHW; 2020.
Australian Bureau of Statistics. Causes of Deaths, Australia, 2016 [internet]. 2017 [cited 2018 25/09]. ABC cat. no. 3303.0,:[Available from: http://www.abs.gov.au/ausstats/abs@.nsf/Lookup/by%20Subject/3303.0~2016~Media%20Release~Drug%20Induced%20Deaths%20Increase%20in%202016%20(Media%20Release)~9].
Pezalla EJ, Rosen D, Erensen JG, Haddox JD, Mayne TJ. Secular trends in opioid prescribing in the USA. J Pain Res. 2017;10:383.
Islam MM, McRae IS. An inevitable wave of prescription drug monitoring programs in the context of prescription opioids: pros, cons and tensions. BMC Pharmacol Toxicol. 2014;15(1):46.
Green TC, Mann MR, Bowman SE, Zaller N, Soto X, Gadea J Jr, et al. How does use of a prescription monitoring program change pharmacy practice? J Am Pharm Assoc. 2013;53(3):273–81.
Maven Marketing. List of Pharmacies and Chemists in Australia. 2019 [Available from: https://www.mavenmarketing.com.au/list-of-pharmacies-in-australia/.
IBISWorld. IBISWorld industry report G4271a. Pharmacies in Australia. Melbourne: IBISWorld Network; 2015.
Nielsen S, Menon N, Larney S, Farrell M, Degenhardt L. Community pharmacist knowledge, attitudes and confidence regarding naloxone for overdose reversal. Addiction. 2016;111(12):2177–86.
Matheson C, Bond CM, Tinelli M. Community pharmacy harm reduction services for drug misusers: national service delivery and professional attitude development over a decade in Scotland. J Public Health. 2007;29(4):350–7.
Matheson C, Bond CM, Mollison J. Attitudinal factors associated with community pharmacists’ involvement in services for drug misusers. Addiction. 1999;94(9):1349–59.
Matheson C, Thiruvothiyur M, Robertson H, Bond C. Community pharmacy services for people with drug problems over two decades in Scotland: implications for future development. Int J Drug Policy. 2016;27:105–12.
Kahan M, Wilson L, Wenghofer EF, Srivastava A, Resnick A, Janecek E, et al. Pharmacists’ experiences with dispensing opioids: provincial survey. Can Fam Physician. 2011;57(11):e448–45454.
Nielsen S, Cameron J, Pahoki S. Opportunities and challenges: over-the-counter codeine supply from the codeine consumer’s perspective. Int J Pharm Pract. 2013;21(3):161–8.
The National Centre on Addiction and Substance Abuse at Columbia University. Under the Counter: the diversion and abuse of controlled prescription drugs in the US. New York; (2005).
Pharmacy Board of Australia. Registrant Data. 2018.
Sheridan J, Butler R. Prescription drug misuse in New Zealand: challenges for primary health care professionals. Res Soc Adm Pharm. 2011;7(3):281–93.
Bono JD, Crawford SY. Impact of medicare part D on independent and chain community pharmacies in rural Illinois—a qualitative study. Res Soc Adm Pharmacy. 2010;6(2):110–20.
Tolhurst H, Baker L, Murray G, Bell P, Sutton A, Dean S. Rural general practitioner experience of work-related violence in Australia. Aust J Rural Health. 2003;11(5):231–6.
Hughes CM, McCann S. Perceived interprofessional barriers between community pharmacists and general practitioners: a qualitative assessment. Br J Gen Pract. 2003;53(493):600–6.
Edwards PJ, Roberts I, Clarke MJ, Diguiseppi C, Wentz R, Kwan I, et al. Methods to increase response to postal and electronic questionnaires. The Cochrane database of systematic reviews. 2009;8(3):Mr000008.
Fincham JE. Response rates and responsiveness for surveys, standards, and the Journal. Am J Pharm Educ. 2008;72(2):43.
Puspitasari HP, Aslani P, Krass I. The influence of pharmacy and pharmacist characteristics on the secondary prevention of cardiovascular disease. Int J Clin pharm. 2015;37(5):834–43.
Funding
SN is a recipient of NHMRC Research Fellowship (#1163961). Data was collected for the original study through an untied educational grant from Indivior. The contents of the published material are solely the responsibility of the authors and do not reflect the funding bodies.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflicts of interest
SN is an investigator on untied educational grants from Indivior that are unrelated to this work. SN is an investigator on research grants from Seqirus unrelated to this work. SN and PW have received honoraria for providing training on identification and treatment of codeine and other opioid dependence (Indivior).
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Alvin, M., Picco, L., Wood, P. et al. Community pharmacists’ preparedness to intervene with concerns around prescription opioids: findings from a nationally representative survey. Int J Clin Pharm 43, 411–419 (2021). https://doi.org/10.1007/s11096-020-01152-8
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11096-020-01152-8