International Journal of Clinical Pharmacy

, Volume 39, Issue 2, pp 483–486 | Cite as

Appropriateness of surgical antibiotic prophylaxis for breast surgery procedures

  • Smeem Jaber
  • Crystal Rogers
  • Bruce Sunderland
  • Richard Parsons
  • Sarah MacKenzie
  • Jason Seet
  • Petra CzarniakEmail author
Short Research Report


Background Guidelines for the appropriate use of antibiotic prophylaxis are provided in the Therapeutic Guidelines: Antibiotics (eTG) in Australia. Inappropriate use of antibiotics is problematic. Objective To examine adherence with therapeutic guidelines (eTG) in breast surgery and trends in non-adherence dependent on the type of breast surgery performed. Setting Major Western Australian teaching hospital. Method A retrospective cross-sectional study reviewed a random sample of 150 from 1049 eligible medical records of patients who underwent a breast surgical procedure in 2013 or 2014. Main outcome measure Adherence to the eTG. Results Antibiotic prophylaxis was prescribed for 139 (92.7%) operations. Adherence to the eTG occurred in 20 (13.3%) operations, whilst 11 (7.3%) did not adhere to any element of the eTG. Appropriate timing was the main factor not adhered to. Postoperative antibiotics were prescribed following 35 (23.3%) operations, with 32 (91.4%) administered beyond 24 h. Length of stay was significantly different (p = 0.0036) between surgical groups. There was a tendency for risk of an infection to be decreased with adherence (odds ratio: 0.23; 95% CI: 0.05, 1.07; p = 0.06). Conclusion Adherence to the eTG was low (13.3%), despite a decreased risk of SSI when guidelines were followed.


Adherence Antibiotic prophylaxis Australia Breast surgery Clinical guidelines 



The authors acknowledge the assistance of the medical records department of the research hospital for their support and assistance.


This study had no special source of funding.

Conflicts of interest

The authors declare that they have no conflicts of interest to disclose.


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Copyright information

© Springer International Publishing 2017

Authors and Affiliations

  1. 1.Curtin UniversityBentleyAustralia
  2. 2.Sir Charles Gairdner HospitalNedlandsAustralia

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