Skip to main content
SpringerLink
Log in

Extraction and Identification of Triterpenoids from Atractylodes ovata (Thunb.) DC.

  • MEDICINAL PLANTS
  • Published:
Pharmaceutical Chemistry Journal Aims and scope

Eight triterpenoids (lupeol, taraxasterol, α-amyrin, β-amyrin, 3-O-acetyllupeol, 3-O-acetyl- α -amyrin, 3-O-acetyl- β-amyrin, and 3-O-acetyltaraxasterol) were identified for the first time in ovate-leaf atractylodes [Atractylodes ovata (Thunb.) DC.] growing in Primorsky Territory of the Russian Far East using 13C NMR spectroscopy and mass spectrometry with electron-impact ionization. The effect of the nature of the extractant (hexane, CCl4 , 95% EtOH) on the yield of triterpenoids from the aboveground and underground organs of A. ovata was studied. The triterpenoids were extracted most from the starting raw material using CCl4 (inflorescences, 4.87%; leaves, 1.41%; roots, 0.25%); least, using EtOH (inflorescences, 2.04%; leaves, 1.25%; roots, 0.10%). The compositions of triterpenoids in extracts of the aboveground and underground organs of A. ovata were determined by GC-MS. Lupeol was shown to be the dominant triterpenoid in leaves and roots of A. ovata (0.39 ± 0.03 and 0.10 ± 0.02%, respectively), whereas 3-O-acetyl- β-amyrin dominated in inflorescences (1.11 ± 0.04%).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. N. K. Fruentov, Medicinal Plants of the Far East [in Russian], Khabarovskoe Knizhnoe Izdatel?stvo, Khabarovsk (1987).

  2. H. Meng, G. Li, R. Dai, et al., Biochem. Syst. Ecol., 38(6), 1220 – 1223 (2010).

    Article  CAS  Google Scholar 

  3. K. T. Wang, L. G. Chen, D. S. Chou, et al., Evidence-based Complementary Altern. Med., 2011, Art. ID 204892 (2011).

  4. J. Kitajima, A. Kamoshita, T. Ishikawa, et al., Chem. Pharm. Bull., 51(9), 1106 – 1108 (2003).

    Article  CAS  Google Scholar 

  5. T. Ishii, T. Okuyama, N. Noguchi, et al., J. Nat. Med., 74, 51 – 64 (2020).

    Article  CAS  PubMed  Google Scholar 

  6. K. T. Wang, L. G. Chen, L. L. Yang, et al., Chem. Pharm. Bull., 55(1), 50 – 56 (2007).

    Article  CAS  Google Scholar 

  7. R. C. Oliviera, P. N. Bandeira, T. G. Lemos, et al., J. Mol. Struct., 1256, 1 – 11 (2022).

    Google Scholar 

  8. U. Holzgrabe, I. Wawer, and B. Diehl, NMR Spectroscopy in Pharmaceutical Analysis, Elsevier Science, Germany (2008).

    Google Scholar 

  9. V. D. Ebajo, Jr., C. C. Shen, and C. Y. Ragasa, J. Appl. Pharm. Sci., 5(4), 33 – 39 (2015).

    Google Scholar 

  10. L. H. Hanh, P. D. Dung, L. D. Huy, et al., Vietnam J. Chem., 58(5), 637 – 642 (2020).

    CAS  Google Scholar 

  11. V. M. Patil, Stud. Nat. Prod. Chem., 72(5), 147 – 199 (2022).

    Article  CAS  Google Scholar 

  12. N. N. Okoye, D. L. Ajaghaku, H. N. Okeke, et al., Pharm. Biol., 52(11), 1478 – 1486 (2014).

    Article  CAS  PubMed  Google Scholar 

  13. Y. Wang, S. Chen, K. Du, et al., J. Ethnopharmacol., 279, 114386 (2021).

    Article  PubMed  Google Scholar 

  14. F. Perez-Garcia, E. Marin, T. Parella, et al., Phytomedicine, 12(4), 278 – 284 (2005).

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

We thank V. G. Savchenko, Head Engineer of the Laboratory for Molecular Analysis, FEFU, for recording the 13C NMR spectra.

Author information

Authors and Affiliations

  1. Far Eastern Federal University, 10 Ajax Bay, Vladivostok, 690950, Russia

    A. V. Myagchilov, L. I. Sokolova, K. S. Kulagina & R. V. Dudkin

  2. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, 159 Prosp. 100 Let Vladivostoku, Vladivostok, 690922, Russia

    A. V. Myagchilov & R. V. Dudkin

Authors
  1. A. V. Myagchilov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. I. Sokolova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. K. S. Kulagina
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. V. Dudkin
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to A. V. Myagchilov.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 57, No. 8, pp. 46 – 50, August, 2023

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Myagchilov, A.V., Sokolova, L.I., Kulagina, K.S. et al. Extraction and Identification of Triterpenoids from Atractylodes ovata (Thunb.) DC.. Pharm Chem J 57, 1271–1276 (2023). https://doi.org/10.1007/s11094-024-03034-z

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11094-024-03034-z

Keywords

Search

Navigation