Phytochemical evaluation of the alcoholic extract of Rubia cordifolia Linn. roots resulted in the identification of two anthraquinone compounds 1a (1,4-dihydroxyanthracene-9,10(4aH,9aH)-dione) and 1b (2-methylanthracene-9,10(4aH,9aH)-dione). The isolated compounds were characterized by spectroscopic methods and their structures were established. The derivatives were found to be nontoxic against Vero and HepG2 cells.
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The authors are thankful to the Chebrolu Hanumaiah Institute of Pharmaceutical Sciences (Guntur), Andhra University (Vishakhapatnam) and Central Electro Chemical Research Institute, (Tamil Nadu) for providing facilities during the project work.
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Srinivasulu, P., Janga, R.B., Kumar, T.N.V.G. et al. Isolation and Cytotoxicity Estimation of Anthraquinone Derivatives from Alcoholic Extract of Rubia cordifolia Linn. Roots. Pharm Chem J 55, 600–603 (2021). https://doi.org/10.1007/s11094-021-02464-3
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DOI: https://doi.org/10.1007/s11094-021-02464-3