The qualitative and quantitative chemical compositions of Astragalus vulpinus Willd. herb were investigated and included saponins, flavonoids, and ascorbic acid. Porsolt tests on white outbred male rats subjected to informational stress were used to study the psychomodulating effect of A. vulpinus herbal extract on their behavior. It was established that extract of A. vulpinus herb produced protective action under informational stress conditions by restoring changes of the psychoemotional status.
Similar content being viewed by others
References
A. M. Meller-Leimkyuller, Sotsial. Klin. Psikhiatr., No. 4, 5 – 11 (2004).
V. A. Bodrov, Informational Stress [in Russian], Per Se, Moscow (2000), pp. 138 – 145.
M. G. Kovtunovich and K. E. Markachev, Psikhol. Nauka Obraz., No. 5, 83 – 91 (2008).
N. I. Medvedeva, Vestn. Sev.-Kavk. Fed. Univ., No. 2 (47), 235 – 239 (2015).
R. D. Seifulla, A. K. Sariev, and D. A. Abaimov, Eksp. Klin. Farmakol., No. 11, 34 – 38 (2010).
R. D. Seifulla and I. M. Kondrashin, Sport. Med. Nauka Prakt., No. 1, 54 – 55 (2011).
D. Siwicka, E. Skopinska-Ryzewska, and P. Bodera, Cent. Eur. J. Immunol., 36(2), 104 – 107 (2011).
A. K. Antonov, O. A. Bocharova, A. V. Belousov, et al., Vestn. Sluzhby Krovi Ross., No. 2, 23 – 26 (2011).
I. G. Nikolaeva, Author’s Abstract of a Doctoral Dissertation in Pharm. Sci., Ulan-Ude (2012).
M. V. Tsymbal, A. T. Grechko, and Yu. K. Antonov, Vestn. Sluzhby Krovi Ross., No. 1, 34 – 36 (2012).
E. B. Khlebtsova, M. A. Samotrueva, M. M. Magomedov, et al., Farmatsiya, No. 3, 46 – 48 (2012).
I. N. Putyrskii and V. N. Prokhorov, Universal Encyclopedia of Medicinal Plants [in Russian], Makhaon, Moscow (2000), pp. 14 – 39.
A. I. Shreter, B. G. Valentinov, and E. M. Naumova, Natural Raw Material of Chinese Medicine [in Russian], Vol. 1, Terevinf, Moscow (2004), pp. 28 – 31.
M. F. Kozak and I. A. Skvortsova, Zdorov’e Obraz. XXI Veke, 14(8), 181 – 182 (2012).
E. T. Batotsyrenova, A. A. Toropova, L. M. Tankhaeva, et al., Vestn. Buryat. Gos Univ., No. 12, 15 – 18 (2012).
N. N. Guzhva, Khim. Rastit. Syr’ya, No. 3, 123 – 132 (2009).
A. A. Toropova, S. V. Lemza, T. A. Azhunova, et al., Vestn. Buryat. Gos. Univ., No. 12, 24 – 27 (2013).
S. T. Kokhan, A. V. Pateyuk, and A. G. Mondodoev, Vestn. Farm., No. 4 (58), 59 – 63 (2012).
I. E. Lobanova and Yu. L. Yakimova, Vestn. Novosib. Gos Univ., 10(2), 79 – 83 (2012).
V. B. Khobrakova and S. M. Nikolaev, Sib. Med. Obozr., No. 5 (59), 45 – 48 (2009).
L. V. Shurygina, A. A. Kravtsov, E. I. Zlishcheva, et al., Vestn. Voronezh. Gos. Univ., No. 4, 149 – 153 (2014).
V. N. Belous, in: Proceedings of the 1st International Scientific- Practical Conference on Analytical Methods of Floristry and Problems of Florogenesis [in Russian], Astrakhan (2012), pp. 140 – 145.
M. U. Sergalieva, M. V. Mazhitova, and M. A. Samotrueva, Astrakh. Med. Zh., No. 2, 17 – 31 (2015).
M. U. Sergalieva, M. V. Mazhitova, and M. A. Samotrueva, Sovrem. Probl. Nauki Obraz., No. 5, (2015); http: // www.science-education.ru / 128-21809 ().
M. V. Leonova and Yu. N. Klimochkin, Extraction Methods for Preparing Drugs from Plant Raw Material: Learning and Teaching Aide [in Russian], Samar. Gos. Tekh. Univ., Samara (2012), pp. 37 – 43.
N. I. Grinkevich and L. N. Safronich, Chemical Analysis of Medicinal Plants [in Russian], Vysshaya Shkola, Moscow (1983), pp. 9 – 89.
Ministry of Health and Social Development of the Russian Federation Order No. 708-n of Aug. 23, 2010 “On approval of good laboratory practice rules.”
M. A. Samotrueva, D. L. Teplyi, and I. N. Tyurenkov, Estestv. Nauki, 27(2), 140 – 152 (2009).
S. Glantz, Primer of Biostatistics, 4th Ed., McGraw-Hill Inc., New York (1997), 473 pp [Russian translation, Praktika, Moscow (1999), pp. 327 – 331].
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 55, No. 2, pp. 40 – 45, February, 2021.
Rights and permissions
About this article
Cite this article
Samotrueva, M.A., Mazhitova, M.V., Sergalieva, M.U. et al. Phytochemical Characteristics of Astragalus vulpinus Willd. Herb and Psychomodulating Activity of its Extract. Pharm Chem J 55, 159–164 (2021). https://doi.org/10.1007/s11094-021-02388-y
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11094-021-02388-y