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CU(II) Complex with Nicotine and Carcinogenicity of Raw Medical Tobacco

Pharmaceutical Chemistry Journal volume 54, pages 1290–1294 (2021)Cite this article

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Unusual coordination of Cu(II) with the pyrrolidine N atom of nicotine in aqueous solution that could promote the formation of carcinogenic N-nitrosonornicotine in raw medical tobacco was shown using circular dichroism.

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Authors and Affiliations

  1. A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilova St., Moscow, 119991, Russia

    K. K. Babievskii, A. B. Uryupin & K. A. Kochetkov

  2. D. I. Mendeleev University of Chemical Technology of Russia, 9 Miusskaya Sq., Moscow, 125047, Russia

    K. A. Kochetkov

Authors
  1. K. K. Babievskii
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  2. A. B. Uryupin
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  3. K. A. Kochetkov
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Corresponding author

Correspondence to A. B. Uryupin.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 54, No. 12, pp. 60 – 64, December, 2020.

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Babievskii, K.K., Uryupin, A.B. & Kochetkov, K.A. CU(II) Complex with Nicotine and Carcinogenicity of Raw Medical Tobacco. Pharm Chem J 54, 1290–1294 (2021). https://doi.org/10.1007/s11094-021-02358-4

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  • DOI: https://doi.org/10.1007/s11094-021-02358-4

Keywords

  • nicotine
  • Cu(II) complexes
  • circular dichroism spectra