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Antidepressant Activity of Flavonoids and Thick Extract from Filipendula ulmaria Fruit

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Pharmaceutical Chemistry Journal Aims and scope

The flavonoids quercetin and spireoside (quercetin 4′-O-β-D-glucopyranoside) were isolated for the first time from fruit of meadowsweet [Filipendula ulmaria (L.) Maxim.] and identified using UV spectrophotometry, NMR spectroscopy, mass spectrometry, and acid hydrolysis. The isolated flavonoids and the thick extract of meadowsweet fruit possessed pronounced antidepressant activity according to the Despair test.

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Authors and Affiliations

  1. Samara State Medical University, Samara, 443009, Russia

    V. A. Kurkin, K. N. Sazanova, E. N. Zaitseva, S. Kh. Sharipova, O. E. Pravdivtseva, E. V. Avdeeva, E. P. Gladunova & N. R. Varina

Authors
  1. V. A. Kurkin
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  2. K. N. Sazanova
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  3. E. N. Zaitseva
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  4. S. Kh. Sharipova
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  5. O. E. Pravdivtseva
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  6. E. V. Avdeeva
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  7. E. P. Gladunova
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  8. N. R. Varina
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Corresponding author

Correspondence to V. A. Kurkin.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 54, No. 8, pp. 10 – 12, August, 2020.

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Kurkin, V.A., Sazanova, K.N., Zaitseva, E.N. et al. Antidepressant Activity of Flavonoids and Thick Extract from Filipendula ulmaria Fruit. Pharm Chem J 54, 797–799 (2020). https://doi.org/10.1007/s11094-020-02276-x

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  • DOI: https://doi.org/10.1007/s11094-020-02276-x

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