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Secondary Metabolite Profiling Via LC-HRMS Q-TOF of Foleyola Billotii, an Endemic Brassicaceae Plant of North-Western Sahara

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Pharmaceutical Chemistry Journal Aims and scope

LC-HRMS Q-TOF method was used to identify and quantify metabolites of Foleyola billotii Maire plant. A series of 15 compounds were tentatively identified: three glucosinolates, 2 aliphatic (progoitrin and gluconapin) and 1 indolic (glucobrassicin); six chlorogenic acids, four coumaroyl quinic acid (CoQA) isomers and two feruloyl quinic acid (FQA) isomers; two diglycosylated flavonols, one quercetin-derived and one kaempferol-derived; three sinapic acid derivatives, sinapoyl threonic acid, hexose sinapate and a third derivative supposedly attributed to a feruloyl quinic acid sinapate; and finally, a glycosylated trans-cinnamic acid which could correspond to feruloylthreonic acid (FTA). Glucosinolates content was 55 times higher in cultivated plants; chlorogenic acids and flavonols increased too by 5 and 3.5 times, respectively. In contrast, sinapates decreased by 3 times in cultivated plants, this last result can be explained by reduced UV-B intensity in the north of Algeria. The change in F. billotii compound profile was more quantitative rather than qualitative.

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Acknowledgments

We would like to thank the Administration of Forests’ Conservation of Tindouf for their precious help and accompanying during plant collection and for providing all necessary information.

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Authors and Affiliations

  1. Laboratory of Plant Physiology, Faculty of biological Sciences, Houari Boumediene University of Sciences and Technology, BP 31, El-Alia, Bab-Ezzouar, 16111, Algiers, Algeria

    Yazid Mahdaoui & Aicha Belkebir

  2. Institut Jean-Pierre Bourgin, UMR1318 INRA-AgroParisTech-ERL3559 CNRS, INRA - Centre de Versailles-Grignon, Batiment 2, Route de Saint-Cyr (RD 10), 78026, Versailles Cedex, France

    François Perreau

  3. Laboratory of Biosystematics, Genetics & Evolution, Faculty of biological Sciences, Houari Boumediene University of Sciences and Technology, BP 32, El-Alia, Bab-Ezzouar, 16111, Algiers, Algeria

    Houria Hadj-Arab

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  1. Yazid Mahdaoui
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  2. François Perreau
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  3. Houria Hadj-Arab
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  4. Aicha Belkebir
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Correspondence to Yazid Mahdaoui.

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Mahdaoui, Y., Perreau, F., Hadj-Arab, H. et al. Secondary Metabolite Profiling Via LC-HRMS Q-TOF of Foleyola Billotii, an Endemic Brassicaceae Plant of North-Western Sahara. Pharm Chem J 54, 734–744 (2020). https://doi.org/10.1007/s11094-020-02264-1

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  • DOI: https://doi.org/10.1007/s11094-020-02264-1

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