Skip to main content
SpringerLink
Log in

Chronic Administration of Methylphenidate Induced Degeneration of Spermatogenesis in Adult Male Rats

  • Published:
Pharmaceutical Chemistry Journal Aims and scope

Apossible mechanism of methylphenidate (MPH) action upon reproductive system, in particular on the fertility rate of male mice, is discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.
Fig. 2.
Fig. 3.
Fig. 4.

Similar content being viewed by others

References

  1. W. A. Morton and G. G. Stockton, Prim. Care Companion J. Clin. Psychiatry, 2(5), 159 (2000).

    Article  PubMed  PubMed Central  Google Scholar 

  2. E. Frauger, et al., Eur. Addict. Res., 22(3), 119 – 126 (2016).

    Article  PubMed  Google Scholar 

  3. H. C. Kimko, J. T. Cross, and D. R. Abernethy, Clin. Pharmacokin., 37(6), 457 – 470 (1999).

    Article  CAS  Google Scholar 

  4. P. B. Danborg, A. L. Simonsen, and P. C. Gøtzsche, Int. J. Risk Saf. Med., 29(1 – 2), 107 – 124 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  5. J. S. Markowitz, et al., J. Child. Adol. Psychopharmacol., 16(6), 687 – 698 (2006).

    Article  Google Scholar 

  6. S. Teo, et al., Toxicology, 179(3), 183 – 196 (2002).

    Article  CAS  PubMed  Google Scholar 

  7. S. Chatterjee-Chakrabarty, et al., Fertil. Steril., 84, 1131 – 1138 (2005).

    Article  CAS  PubMed  Google Scholar 

  8. S. Fazelipour, et al., J. Reprod. Infertil., 13(4), 232 (2012).

    CAS  PubMed Central  PubMed  Google Scholar 

  9. , H. A, Spiller, H. L. Hays, and A. Aleguas, CNS Drugs, 27(7), 531 – 543 (2013).

    Article  Google Scholar 

  10. J.-Y. Shin, et al., BMJ, 353, i2550 (2016).

    Google Scholar 

  11. C. R. González, et al., PLos One, 10(11), E0142713 (2015).

    Google Scholar 

  12. Á. Garcia-Avulés, et al., Asian J. Androl., 9, 33 (2015).

    Google Scholar 

  13. T. Grund, et al., Brain Res. J., 1176, 124 – 132 (2007).

    Article  CAS  Google Scholar 

  14. M. Reed, C. Howard, and G. S. De Yanés, J. Microsc., 239(1), 54 – 65 (2010).

    Article  CAS  PubMed  Google Scholar 

  15. H. LI et al., J. Environ. Pathol. Toxicol. Oncol., 18(1), 73 – 77 (1999).

    PubMed  Google Scholar 

  16. J. Chin, et al., Brain Res. J., 945(1), 123 – 130 (2002).

    Article  CAS  Google Scholar 

  17. G. S. Yang, et al., Asian J. Androl., 8(5), 569 – 575 (2006).

    Article  CAS  PubMed  Google Scholar 

  18. B. G. Montagnini, et al., Physiol. Behav., 133, 122 – 129 (2014).

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

This research project was performed in the Biology and Anatomical Sciences Department, Shahid Beheshti University of Medical Sciences, and was supported by the Vice Chancellor of Research of the Shahid Beheshti University of Medical Sciences.

CONFLICT OF INTEREST

The authors declare that they have no conflict of interest.

Author information

Author notes

  1. Mohammad-Amin Abdollahifar and Moein Zangiabadian contributed equally to this work.

Authors and Affiliations

  1. Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Theran, Iran

    Mohammad-Amin Abdollahifar, Moein Zangiabadian, Ali Moradi, Fatereh Rezaei, Sina Fadai, Aysan Khatmi, Samira Ezi, Mohsen Norozian, Yasaman Razminia, Sara Fazli & Abbas Aliaghaei

  2. Department of Anatomical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran

    Meysam Hassani Moghoddam

Authors
  1. Mohammad-Amin Abdollahifar
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Moein Zangiabadian
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ali Moradi
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Fatereh Rezaei
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Sina Fadai
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Aysan Khatmi
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Samira Ezi
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Mohsen Norozian
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Meysam Hassani Moghoddam
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Yasaman Razminia
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. Sara Fazli
    View author publications

    You can also search for this author in PubMed Google Scholar

  12. Abbas Aliaghaei
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Mohsen Norozian.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Abdollahifar, MA., Zangiabadian, M., Moradi, A. et al. Chronic Administration of Methylphenidate Induced Degeneration of Spermatogenesis in Adult Male Rats. Pharm Chem J 54, 689–693 (2020). https://doi.org/10.1007/s11094-020-02257-0

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11094-020-02257-0

Keywords

Search

Navigation