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Synthesis and Antimicrobial Activity of 5-(Arylmethylidene)-2,4,6-Pyrimidine-2,4,6(1H,3H,5H)-Triones

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A series of 5-(arylmethylidene)-2,4,6-pyrimidine-2,4,6(1H,3H,5H)-triones were synthesized and tested for antimicrobial activity against Staphylococcus and Streptococcus bacteria strains.

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The work was financially supported by the program “Development of Innovative Infrastructure in Russian Institutions of Higher Education” (Grant No. 13.637.31.0038); used equipment at the Green Chemistry Scientific Educational Center of Astrakhan State University; and was sponsored by the Ministry of Education and Science of the RF, Grant No. 115021010181.

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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 52, No. 6, pp. 18 – 21, June, 2018.

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Luzhnova, S.A., Tyrkov, A.G., Gabitova, N.M. et al. Synthesis and Antimicrobial Activity of 5-(Arylmethylidene)-2,4,6-Pyrimidine-2,4,6(1H,3H,5H)-Triones. Pharm Chem J 52, 506–509 (2018).

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