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Synthesis and Antimicrobial Activity of 5-(Arylmethylidene)-2,4,6-Pyrimidine-2,4,6(1H,3H,5H)-Triones

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A series of 5-(arylmethylidene)-2,4,6-pyrimidine-2,4,6(1H,3H,5H)-triones were synthesized and tested for antimicrobial activity against Staphylococcus and Streptococcus bacteria strains.

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References

  1. S. A. Luzhnova, A. G. Tyrkov, N. M. Gabitova, and E. A. Yurtaeva, Khim.-farm. Zh., 49(12), 12 – 14 (2015); Pharm. Chem. J., 49(12), 810 – 812 (2016).

    Google Scholar 

  2. T. T. Anastas and J. C. Warner, Green Chemistry: Theory and Practice, Oxford University Press, New York (1998), p. 25.

    Google Scholar 

  3. E. Pretsch, P. Buhlmann, and C. Affolter, Structure Determination of Organic Compounds, Springer, Berlin, New York (2000) [Russian translation, Mir, Moscow (2006), pp. 393 – 395].

    Book  Google Scholar 

  4. A. A. Potekhin, Properties of Organic Compounds [in Russian], Khimiya, Leningrad (1984), p. 296.

    Google Scholar 

  5. J. G. Kirchner, Techniques of Chemistry, Vol. 14: Thin-Layer Chromatography, 2nd Ed., Wiley-Interscience, New York (1978), 1137 pp [Russian translation, Mir, Moscow (1981), pp. 129, 218].

    Google Scholar 

  6. P. Gerhardt, Manual of Methods for General Bacteriology, American Society for Microbiology, Washington DC (1981) [Russian translation, Mir, Moscow (1983), Vol. 2, p. 29].

  7. S. M. Navashin and I. P. Fomin, Reference Book on Antibiotics [in Russian], Meditsina, Moscow (1974), p. 54.

    Google Scholar 

  8. A. N. Kalyuk, Methods of Bacteriological Research in Clinical Microbiology, Methodical Recommendations [in Russian], Moscow (1983), p. 15.

  9. M. D. Mashkovskii, Drugs [in Russian], Novaya Volna, Moscow (2006), pp. 783 – 784, 833.

  10. V. G. Granik, Principles of Medicinal Chemistry [in Russian], Vusovskaya Shkola, Moscow (2001), p. 38.

    Google Scholar 

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Acknowledgments

The work was financially supported by the program “Development of Innovative Infrastructure in Russian Institutions of Higher Education” (Grant No. 13.637.31.0038); used equipment at the Green Chemistry Scientific Educational Center of Astrakhan State University; and was sponsored by the Ministry of Education and Science of the RF, Grant No. 115021010181.

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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 52, No. 6, pp. 18 – 21, June, 2018.

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Luzhnova, S.A., Tyrkov, A.G., Gabitova, N.M. et al. Synthesis and Antimicrobial Activity of 5-(Arylmethylidene)-2,4,6-Pyrimidine-2,4,6(1H,3H,5H)-Triones. Pharm Chem J 52, 506–509 (2018). https://doi.org/10.1007/s11094-018-1849-7

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  • DOI: https://doi.org/10.1007/s11094-018-1849-7

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