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Synthesis and Conversions of Polyhedral Compounds. 32. Synthesis and Antibacterial Activity of Azaadamantane-Containing Azomethine Dihydrochlorides

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Pharmaceutical Chemistry Journal Aims and scope

New azomethines (Schiff bases) containing azaadamantane groups on one side and several biologically active compounds on the other were synthesized. The antibacterial activity of their dihydrochlorides showed that azomethines containing a nitrofuryl group were most active.

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References

  1. G. L. Arutyunyan, R. V. Paronikyan, K. A. Gevorkyan, et al., Khim.-farm. Zh., 42(1), 20 – 23 (2008); Pharm. Chem. J., 42(1), 18 – 22 (2008).

  2. G. L. Arutyunyan, K. A. Gevorkyan, A. D. Arutyunyan, et al., Khim. Geterotsikl. Soedin., No. 11, 1786 – 1791 (2012).

  3. N. W. Gabel, US Pat. 3,301,854, Jan. 31, 1967; Chem. Abstr., 67, 2193h (1967).

  4. N. S. Egorov, Study Principles for Antibiotics [in Russian], Vysshaya Shkola, Moscow (1979), p. 179.

    Google Scholar 

  5. A. N. Mironov, N. D. Bunatyan, et al., Handbook for Preclinical Drug Trials [in Russian], Ministerstvo Zdravookhraneniya i Sotsial’nogo Razvitiya RF [RF Ministry of Health and Social Development], FGBU Nauchnyi Tsentr Ekspertizy Sredstv Meditsinskogo Primeneniya [Scientific Centre for Expert Examination of Medicinal Products], Moscow, 2012.

  6. M. D. Mashkovskii, Drugs [in Russian], Novaya Volna, Moscow (2010), p. 858.

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Correspondence to G. L. Arutyunyan.

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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 52, No. 5, pp. 37 – 41, May, 2018.

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Arutyunyan, G.L., Arutyunyan, A.D., Gevorkyan, K.A. et al. Synthesis and Conversions of Polyhedral Compounds. 32. Synthesis and Antibacterial Activity of Azaadamantane-Containing Azomethine Dihydrochlorides. Pharm Chem J 52, 419–423 (2018). https://doi.org/10.1007/s11094-018-1834-1

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  • DOI: https://doi.org/10.1007/s11094-018-1834-1

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