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Benzimidazole Ring System as a Privileged Template for Anticancer Agents

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Pharmaceutical Chemistry Journal Aims and scope

Cancer still remains a continued threat for human race in the 21st century. It is the major cause of human casualties globally and is thus, a hot topic of research in medicinal laboratories. Scientists are striving to find selective anticancer agents having low toxicity for normal human cells. Heterocyclic ring systems play key role as templates/pharmacophores for various drugs, and benzimidazole ring is especially important for its anticancer derivatives. In this review article, we have focused on the structural features of anticancer derivatives based on benzimidazole ring system. It highlights various benzimidazole-based anticancer compounds which have been developed in recent years.

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Acknowledgements

Some authors (A. K. and M. A.) greatly acknowledge the Higher Education Commission of Pakistan for financial support through research project No. 20-3715/NRPU/R&D/HEC/14/162.

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Authors and Affiliations

  1. Department of Chemistry, Government College University, Faisalabad, 38000, Pakistan

    Afshan Kanwal, Furqan Ahmad Saddique, Matloob Ahmad & Ameer Fawad Zahoor

  2. Department of Chemistry, Government College Women University, Faisalabad, 38000, Pakistan

    Sana Aslam

  3. Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, 38000, Pakistan

    Noor-ul-Amin Mohsin

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  1. Afshan Kanwal
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  2. Furqan Ahmad Saddique
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Correspondence to Matloob Ahmad.

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Kanwal, A., Saddique, F.A., Aslam, S. et al. Benzimidazole Ring System as a Privileged Template for Anticancer Agents. Pharm Chem J 51, 1068–1077 (2018). https://doi.org/10.1007/s11094-018-1742-4

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  • DOI: https://doi.org/10.1007/s11094-018-1742-4

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