The antimicrobial activity of 1,2,5-trimethylpiperidin-4-ols (I – IV) against 20 test microorganisms was studied. 1,2,5-Trimethyl-4-(1′,2′-dihydroxyethyl)piperidin-4-ol benzoate hydrochloride (III) had the widest spectrum of antimicrobial activity (active against 16 test microorganisms) and is suitable for further testing of antimicrobial activity.
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References
Russian Federation Patent RF 1262908; Republic of Kazakhstan Patent No. 527; Byul. Izobret. RK, No. 1 (1994).
Russian Federation Patent RF 1704417; Republic of Kazakhstan Patent No. 3146; Byul. Izobret. RK, No. 1 (1996).
M. D. Mashkovskii, Medicines [in Russian], Novaya Volna, Moscow (2002), Vol. 1, p. 608.
A. G. Serikovna, Izv. Tomskogo Politekhnicheskogo Universiteta, 317(3), 144 – 146 (2010).
L. Naicker, K. Narayanaswamy, F. Shode, and B. Odhav, J. Pharmacy Pharmacol., 9(31), 783 – 792 (2015).
S. Gangadhara, C. Prasad, and P. Venkateswarlu, Indo. Am. J. Pharm. Res., 5(3), 1280 – 1287 (2015).
M. A. Dyusebaeva and S. N. Kalugin, Rus. J. General Chem., 7(85), 1775 – 1778 (2015).
M. A. Dyusebaeva, Zh. Zhenis, and Sh. S. Akhmedova, Vest. KazNU, Ser. Khim., 1, 40 – 43 (2015).
S. N. Kalugin, Author’s Abstract of Master’s Thesis in Chemical Sciences [in Russian], Almaty (1998).
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 51, No. 7, pp. 28 – 29, July, 2017.
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Dyusebaeva, M.A., Elibaeva, N.S. & Kalugin, S.N. Antimicrobial Activity of 1,2,5-Trimethylpiperidin-4-Ol Derivatives. Pharm Chem J 51, 550–552 (2017). https://doi.org/10.1007/s11094-017-1652-x
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DOI: https://doi.org/10.1007/s11094-017-1652-x