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New Flavonoids from Serratula coronata L.

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Pharmaceutical Chemistry Journal Aims and scope

The composition of flavonoids (glycosides) isolated from leaves of Serratula coronata L. s. l. (crowned saw-wort) growing in Primorsky Krai was investigated. Liquid extraction and preparative column chromatography isolated for the first time the flavonoids 3-methylquercetin-3′-O-β-D-glucuronopyranoside [5-(5,7-dihydroxy-3-methoxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenylhexopyranosideuronic acid] and quercetin- 3′-O-β-D-glucuronopyranoside [2-hydroxy-5-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenylhexopyranosideuronic acid]. The structures of the isolated compounds were elucidated and proved using UV and NMR spectroscopy and mass spectrometry with electrospray ionization. The flavonoid 3-methylquercetin-3′-O-β-D-glucuronopyranoside was new and not previously described in the literature. S. coronata grows abundantly in Primorsky Krai and could be considered a renewable and promising source for producing flavonoids.

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Authors and Affiliations

  1. Far-Eastern Federal University, 27 Oktyabr’skaya St., Vladivostok, 690950, Russia

    A. V. Myagchilov, L. I. Sokolova & P. G. Gorovoi

  2. G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch, Russian Academy of Sciences, 159 100-Let Vladivostoku Prosp., Vladivostok, 690922, Russia

    P. S. Dmitrenok

Authors
  1. A. V. Myagchilov
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  2. L. I. Sokolova
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  3. P. G. Gorovoi
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  4. P. S. Dmitrenok
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 51, No. 2, pp. 23 – 27, February, 2017.

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Myagchilov, A.V., Sokolova, L.I., Gorovoi, P.G. et al. New Flavonoids from Serratula coronata L.. Pharm Chem J 51, 119–123 (2017). https://doi.org/10.1007/s11094-017-1568-5

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  • DOI: https://doi.org/10.1007/s11094-017-1568-5

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