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Synthesis and Structure of 7-Hydroxy-5-Oxo-2,3-Dihydro-5H-[1,3]Thiazolo[3,2-a]-Pyrimidine-6-Carboxylic Acid Ethyl Ester

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Pharmaceutical Chemistry Journal Aims and scope

An effective method was developed for the preparation and x-ray diffraction analysis of the spatial structure of 7-hydroxy-5-oxo-2,3-dihydro-5H-[1, 3]thiazolo[3,2-a]pyrimidine-6-carboxylic acid ethyl ester, which is of interest as a starting material for the synthesis of new, potentially biologically active derivatives of thiazolo[3,2-a]pyrimidine hydrogenated in the thiazole part of the molecule.

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Authors and Affiliations

  1. National Pharmaceutical University, Kharkov, Ukraine

    I. V. Ukrainets, L. A. Grinevich & T. V. Alekseeva

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  1. I. V. Ukrainets
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  2. L. A. Grinevich
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  3. T. V. Alekseeva
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 51, No. 1, pp. 42 – 45, January, 2017.

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Ukrainets, I.V., Grinevich, L.A. & Alekseeva, T.V. Synthesis and Structure of 7-Hydroxy-5-Oxo-2,3-Dihydro-5H-[1,3]Thiazolo[3,2-a]-Pyrimidine-6-Carboxylic Acid Ethyl Ester. Pharm Chem J 51, 56–59 (2017). https://doi.org/10.1007/s11094-017-1557-8

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  • DOI: https://doi.org/10.1007/s11094-017-1557-8

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