Pharmaceutical Chemistry Journal

, Volume 50, Issue 9, pp 577–579 | Cite as

Pharmacokinetics of the Polyaldehyde Dextran Conjugate with Isonicotinic Acid Hydrazide

  • A. A. Starostenko
  • V. S. Medvedev
  • A. V. Troitskii
  • T. N. Bystrova
  • S. A. Arkhipov
  • V. A. Shkurupii
Article
  • 43 Downloads

The pharmacokinetics of the promising antituberculosis drug dextrazide, the conjugate of polyaldehyde dextran with isonicotinic acid hydrazide, were studied using outbred ICR mice. The obtained results were indicative of two-phase dextrazide pharmacokinetics.

Keywords

dextrazide pharmacokinetics polyaldehyde dextran 

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • A. A. Starostenko
    • 1
  • V. S. Medvedev
    • 1
  • A. V. Troitskii
    • 1
  • T. N. Bystrova
    • 1
  • S. A. Arkhipov
    • 1
  • V. A. Shkurupii
    • 1
  1. 1.Research Institute of Experimental and Clinical Medicine, Siberian Branch, Russian Academy of Medical SciencesNovosibirskRussia

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