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Vinpocetine Release From a Microencapsulated Form

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Pharmaceutical Chemistry Journal Aims and scope

Microencapsulated vinpocetine was produced by liquid—liquid dispersion using a mixture of beeswax and cocoa oil in a 3:2 ratio as the carrier. The dispersion media were purified H2O and sodium carboxymethylcellulose (Na-CMC) solution (2%). Drug release from the microcapsules was studied in vitro as a function of microcapsule size, shell material, and dispersion medium. The best characteristics were observed for microcapsules with a hydrophobic coating containing beeswax and cocoa oil in a 3:2 ratio of size 0.5 – 1 mm that were produced in Na-CMC solution (2%).

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Acknowledgments

The research was sponsored by the RF President Council on Grants, Grant MK-3317.2015.7.

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Authors and Affiliations

  1. Voronezh State University, 3 Studencheskaya St., Voronezh, 394006, Russia

    Yu. A. Polkovnikova & A. I. Slivkin

Authors
  1. Yu. A. Polkovnikova
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  2. A. I. Slivkin
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Correspondence to Yu. A. Polkovnikova.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 50, No. 8, pp. 56 – 58, August, 2016.

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Polkovnikova, Y.A., Slivkin, A.I. Vinpocetine Release From a Microencapsulated Form. Pharm Chem J 50, 553–555 (2016). https://doi.org/10.1007/s11094-016-1488-9

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  • DOI: https://doi.org/10.1007/s11094-016-1488-9

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