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Development of Manufacturing Technology for Prolonged-Release Oral Amben Preparation

  • DRUG SYNTHESIS METHODS AND MANUFACTURING TECHNOLOGY
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Pharmaceutical Chemistry Journal Aims and scope

Results from technology development for manufacturing an amben prolonged-release preparation based on a Kollidon SR hydrophobic polymer matrix were presented. It was shown that dry and wet granulation could improve the processing properties of mixtures for preparing tablets and provide the required amben release kinetics.

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Acknowledgments

The work was supported financially by the RF Ministry of Education and Science (Contract No. 02.G25.31.0001) under the auspices of RF Administration Decree No. 218 of Apr. 9, 2010, and utilized equipment of the Center for Collective Use of Unique Scientific Equipment for MPTI nanotechnology studies.

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Authors and Affiliations

  1. Life Sciences Center, Moscow Institute of Physics and Technology (Technical University), Dolgoprudnyi, Moscow Oblast, 141700, Russia

    G. O. Nifontova & S. P. Krechetov

  2. I. M. Sechenov First Moscow State Medical University, Moscow, 119991, Russia

    G. O. Nifontova & I. I. Krasnyuk

  3. Moscow Institute of Physics and Technology (Technical University), Dolgoprudnyi, Moscow Oblast, 141700, Russia

    E. V. Korostylev

  4. Farmzashchita Research and Production Center, Federal Medico-Biological Agency of the Russian Federation, Khimki, Moscow Oblast, 141402, Russia

    A. R. Akhmetzyanova

Authors
  1. G. O. Nifontova
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  2. S. P. Krechetov
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  3. E. V. Korostylev
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  4. A. R. Akhmetzyanova
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  5. I. I. Krasnyuk
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Corresponding author

Correspondence to G. O. Nifontova.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 50, No. 8, pp. 39 – 44, August, 2016.

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Nifontova, G.O., Krechetov, S.P., Korostylev, E.V. et al. Development of Manufacturing Technology for Prolonged-Release Oral Amben Preparation. Pharm Chem J 50, 537–542 (2016). https://doi.org/10.1007/s11094-016-1485-z

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  • DOI: https://doi.org/10.1007/s11094-016-1485-z

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