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Synthesis and Anticonvulsive Activity of 5-Pyrrolidin-1-Ylpyrano[4″,3″:4′,5′]Pyrido-3′,2′:4,5]Thieno[3,2-D]Pyrimidine Derivatives

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Pharmaceutical Chemistry Journal Aims and scope

A method for preparing the amino, alkoxy, and alkylsulfanyl derivatives of pyrano[4″,3″:4′,5′]pyrido-[3′,2′:4,5]thieno[3,2-d]pyrimidines based on 8-chloro-2,2-dimethyl-5-pyrrolidin-1-yl-1,4-dihydro-2H-pyrano[4″,3″:4′,5′]pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine was developed. The anticonvulsant activity of the compounds synthesized here was investigated.

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Authors and Affiliations

  1. Institute of Fine Organic Chemistry, Science and Technology Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia, Yerevan, Armenia

    Sh. Sh. Dashyan, E. G. Paronikyan, A. S. Noravyan & R. G. Paronikyan

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  1. Sh. Sh. Dashyan
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  2. E. G. Paronikyan
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  3. A. S. Noravyan
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  4. R. G. Paronikyan
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 50, No. 4, pp. 15 – 18, April, 2016.

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Dashyan, S.S., Paronikyan, E.G., Noravyan, A.S. et al. Synthesis and Anticonvulsive Activity of 5-Pyrrolidin-1-Ylpyrano[4″,3″:4′,5′]Pyrido-3′,2′:4,5]Thieno[3,2-D]Pyrimidine Derivatives. Pharm Chem J 50, 221–225 (2016). https://doi.org/10.1007/s11094-016-1426-x

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  • DOI: https://doi.org/10.1007/s11094-016-1426-x

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