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M-Dinitroaromatic Moiety as a Fragment of Biologically Active Compounds

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Pharmaceutical Chemistry Journal Aims and scope

Data on the biological activities of compounds containing m-dinitroaromatic (m-DAr) moieties were presented and led to the conclusion that including this moiety in the structures of new biologically active compounds was promising. It was established that one nitro group in m-DAr could be replaced by trifluoromethyl without losing the biological activity of the obtained analogs.

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  1. Shchelkovo-Agrokhim Company, 2 Zavodskaya St., Shchelkovo, Moscow, Oblast, 141101, Russia

    V. B. Piskov, V. P. Chernyshev & S. D. Karakotov

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  1. V. B. Piskov
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  2. V. P. Chernyshev
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  3. S. D. Karakotov
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 49, No. 11, pp. 8 – 17, November, 2015.

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Piskov, V.B., Chernyshev, V.P. & Karakotov, S.D. M-Dinitroaromatic Moiety as a Fragment of Biologically Active Compounds. Pharm Chem J 49, 724–734 (2016). https://doi.org/10.1007/s11094-016-1361-x

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