The synthesis of novocainamide by hydrogenation of 4-nitro-N-[2-(diethylamino)ethyl]benzamide on Pd-containing anion exchangers was studied. An improved method for synthesizing novocainamide under mild conditions that was more efficient than the industrial method was proposed based on the experimental results.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 49, No. 2, pp. 50 – 51, February, 2015.
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Abdullaev, M.G., Gebekova, Z.G. Synthesis of Novocainamide by Hydrogenation of 4-Nitro-N-[2-(Diethylamino)Ethyl]Benzamide on Pd-Containing Anion Exchangers. Pharm Chem J 49, 120–121 (2015). https://doi.org/10.1007/s11094-015-1233-9
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DOI: https://doi.org/10.1007/s11094-015-1233-9