We report here the synthesis of a series of imidazolinylhydrazones of salicylaldehyde and their substituted 2-N-tosylaminobenzaldehyde, 2-diphenylphosphinobenzaldehyde, and diacetylmonooxime derivatives, as well as the bis-imidazolinylhydrazones of 2,6-diformyl-4-tert-butylphenol and 2,6-diacetylpyridine. The protistocidal and antibacterial activities of the compounds made here were studied, and some were found to have high levels of protistocidal activity.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
S. Rollas and S. G. Kucukguzel, Molecules, 12(8), 1910 – 1939 (2007).
V. A. Kogan, S. I. Levchenkov, L. D. Popov, and I. N. Shcherbakov, Ros. Khim. Zh., 53(1), 86 – 93 (2009).
N. E. Madadi, P. Vanelle, J. Maldonado, et al., Boll. Chim. Farm., 130(4), 124 – 127 (1991).
M. A. Iradyan, R. A. Aroyan, G. M. Stepanyan, et al., Khim.- Farm. Zh., 42(7), 10 – 11 (2008); Pharm. Chem. J., 42(7), 384 – 386 (2008).
M. Varache-Lembige, S. Moreau, S. Larrouture, et al., Eur. J. Med. Chem., 43(6), 1336 – 1339 (2008).
A. Kornicka, A. L. Hudson, P. J. Bednarski, Acta Pol. Pharm., 66(5), 523 – 534 (2009).
G. Visbal, G. San-Blas, A. Maldonado, et al., Steroids, 76(10 – 11), 1069 – 1081 (2011).
S. I. Levchenkov, L. D. Popov, I. N. Shcherbakov, et al., Koordinats. Khimiya, 39(7), 393 – 399 (2013).
A. Kornicka, M. Gdaniec, Heterocycles, 71(9), 1907 – 1917 (2007).
A. F. Klimenko, L. N. Fetisov, A. A. Zubenko, et al., Vet. Patol., No. 1 – 2, 35 – 40 (2011).
Methods in Experimental Chemotherapy [in Russian], G. N. Pershin (ed.), Meditsina, Moscow (1971), pp. 100 – 106.
This study was supported by the Russian Foundation for Basic Research (Grant No. 12-03-31691).
Author information
Authors and Affiliations
Additional information
Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 49, No. 1, pp. 23 – 25, January, 2015.
Rights and permissions
About this article
Cite this article
Popov, L.D., Levchenkov, S.I., Zubenko, A.A. et al. Synthesis, Protistocidal and Antibacterial Activities of 2′-Imidazolinylhydrazones of Mono- and Dicarboxylic Acids. Pharm Chem J 49, 21–23 (2015). https://doi.org/10.1007/s11094-015-1215-y
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11094-015-1215-y