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Reaction of an Antioxidant (Sodium Sulfite) with 3-Hydroxy-6-Methyl-2-Ethylpyridinium Salts

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An Erratum to this article was published on 01 May 2015

The reaction of an antioxidant excipient (sodium sulfite) with 3-hydroxy-6-methyl-2-ethylpyridinium hydrochloride drug substance was studied using thermal analysis of the solid drug substances and biological testing on cell culture (Spirotox model) in aqueous solutions of various isotopic compositions.

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Authors and Affiliations

  1. Department of Pharmaceutical and Toxicological Chemistry, People’s Friendship University of Russia, 8 Miklukho-Maklaya Ul., Moscow, 117198, Russia

    O. V. Timorovich, E. B. Lyulina, T. V. Pleteneva, T. V. Maksimova & E. V. Uspenskaya

  2. Institute of Applied Geophysics, 9 Rostokinskaya Ul., Moscow, 129128, Russia

    A. V. Syroeshkin

  3. Legkaya Voda Co., 1 Malaya Yushun’skaya Ul., Bldg. 1, Moscow, 117303, Russia

    T. N. Burdeinaya

  4. A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences; Laboratory of Polymer Modification, 29 Leninskii Prosp., Moscow, 119991, Russia

    G. A. Shandryuk

Authors
  1. O. V. Timorovich
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  2. E. B. Lyulina
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  3. T. V. Pleteneva
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  4. T. V. Maksimova
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  5. A. V. Syroeshkin
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  6. E. V. Uspenskaya
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  7. T. N. Burdeinaya
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  8. G. A. Shandryuk
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Corresponding author

Correspondence to O. V. Timorovich.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 48, No. 12, pp. 51 – 53, December, 2014.

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Timorovich, O.V., Lyulina, E.B., Pleteneva, T.V. et al. Reaction of an Antioxidant (Sodium Sulfite) with 3-Hydroxy-6-Methyl-2-Ethylpyridinium Salts. Pharm Chem J 48, 840–842 (2015). https://doi.org/10.1007/s11094-015-1206-z

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  • DOI: https://doi.org/10.1007/s11094-015-1206-z

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