New data for the antioxidant properties of the food plants Allium schoenoprasum and Rubus chamaemorus growing in the Komi Republic were obtained. The activity of the extracts on live bacteria under oxidative stress was studied. It was found that extracts of R. chamaemorus fruit and A. schoenoprasum bulbs had the greatest antioxidant effect and elevated antioxidant activity that was sufficient to protect the bacteria from peroxide stress. These extracts were shown to exhibit antioxidant activity on the bacteria simultaneously via several different pathways including direct inhibition of reactive oxygen species, chelation of iron ions, and induction of antioxidant genes. It was demonstrated for the first time that the ability of the extracts to activate OxyR-regulon genes and to affect the activity of the RpoS-controlled system of general oxidative stress response contributed significantly to the antioxidant activity of the studied extracts in bacteria cultures.
Similar content being viewed by others
References
V. A. Baraboi, Valeology: Diagnostics, Agents, and Wellness Practice: Coll. Sci. Works [in Russian], No. 1, St. Petersburg (1993), pp. 107 – 115.
O. Oktyabrsky, G. Vysochina, N. Muzyka, et al., J. Appl. Microbiol., 106(4), 1175 – 1183 (2009).
G. V. Smirnova, G. I. Vysochina, N. G. Muzyka, et al., Prikl. Biokhim. Mikrobiol., 45(6), 705 – 709 (2009).
G. Smirnova, G. Vysochina, N. Muzyka, et al., World J. Microbiol. Biotechnol., 26(12), 2269 – 2276 (2010).
V. D. Kaz’min, Medicinal Properties of Vegetables, Fruits, and Berries [in Russian], Feniks, Moscow (2007).
B. Thiem, Biol. Lett., 40(1), 3 – 13 (2003).
N. Yu. Kolbas and V. N. Reshetnikov, Tr. BGU, 6(1), 136 – 143 (2011).
R. A. Moyer, K. E. Hummer, C. E. Finn, et al., J. Agric. Food Chem., 50(3), 519 – 525 (2002).
M. Netzel, G. Netzel, Q. Tian, et al., J. Agric. Food Chem., 54(26), 9820 – 9826 (2006).
E. Sariburun, S. Sahin, C. Demir, et al., J. Food Sci., 75(4), 328 – 335 (2010).
N. V. Matistov, O. E. Valuiskikh, and T. I. Shirshova, Izv. Komi Nauchn. Tsentra UrO Ross. Akad. Nauk, No. 1, 41 – 45 (2012).
T. I. Shirshova and G. A. Volkova, Rastit. Resur., 42(3), 59 – 66 (2006).
T. I. Shirshova, I. V. Beshlei, N. V. Matistov, et al., Rastit. Resur., 47(1), 112 – 118 (2011).
T. I. Shirshova, N. A. Golubkina, I. V. Beshlei, et al, Izv. Komi Nauchn. Tsentra UrO Ross. Akad. Nauk, No. 3, 48 – 54 (2011).
D. Steiner, J. Canadanovic-Brunet, and A. Pavlovic, Phytother. Res., 18(7), 522 – 524 (2004).
D. Steiner, B. M. Popovic, D. Calic-Dragosavac, et al., Phytother. Res., 25(11), 1618 – 1622 (2011).
T. I. Shirshova, I. V. Beshlei, V. P. Deryagina, et al., Khim.-farm. Zh., 46(11), 40 – 43 (2012).
L.-F. Shyur, J.-H. Tsung, J.-H. Chen, et al., Int. J. Appl. Sci. Eng. Technol., 3(3), 195 – 202 (2005).
H.-J. Kim, F. Chen, X. Wang, et al., J. Agric. Food Chem., 53, 7691 – 7695 (2005).
L.-C. Wu, H.-W. Hsu, Y.-C. Chen, et al., Food Chem., 95(2), 319 – 327 (2006).
J. H. Miller, Experiments in Molecular Genetics [Russian translation].
J. H. Miller, Experiments in Molecular Genetics, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York (1972), pp. 352 – 355.
G. Storz and J. A. Imlay, Curr. Opin. Microbiol., 2, 188 – 194 (1999).
P. C. Loewen and R. Hengge-Aronis, Annu. Rev. Microbiol., 48, 53 – 80 (1994).
Acknowledgments
The work was supported financially by a grant of the Integrated Research Program, UrB, RAS, No. 12-I-4-2072, and partially by RFBR-Ural Grant No. 10-04-96017.
Author information
Authors and Affiliations
Additional information
Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 48, No. 2, pp. 36 – 40, February, 2014.
Rights and permissions
About this article
Cite this article
Bezmaternykh, K.V., Shirshova, T.I., Beshlei, I.V. et al. Antioxidant Activity of Extracts from Allium Schoenoprasum L. and Rubus Chamaemorus L. Growing in the Komi Republic. Pharm Chem J 48, 116–120 (2014). https://doi.org/10.1007/s11094-014-1060-4
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11094-014-1060-4