Skip to main content
SpringerLink
Log in

A Total Triterpene Glycosides Preparation from Zygophyllum Oxianum as a Potential Hypoglycemic Agent

  • Medicinal Plants
  • Published:
Pharmaceutical Chemistry Journal Aims and scope

Extraction of a total triterpene glycosides preparation from Zygophyllum oxianum and its influence on blood sugar levels in rats with alloxan hyperglycemia and alloxan diabetes are addressed. This preparation had marked hypoglycemic actions on prophylactic and therapeutic administration. The mechanism of action is different from that of the known drug used for the treatment of diabetes Maninil.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. The Flora of Uzbekistan [in Russian], Uzbek SSR Academy of Sciences Press, Tashkent (1959), Vol. IV.

  2. K. H. Batanouny and N. H. Ezzat, Oecologia, No. 7, 170–183 (1971).

  3. M. M. Shabana, Y. W. Mirhom, A. A. Genanah, et al., Arch. Exp. Vet. Med., 44(3), 389–394 (1990).

    CAS  Google Scholar 

  4. F. Skim, B. H. Lazrek, H. El Amri, et al., Phytother. Res., 12(8), 592–594 (1998).

    Article  Google Scholar 

  5. S. A. Sheweita, A. A. Newairy, H. A. Mansour, and M. I. Yousef, Toxicology, 174(2), 131–139 (2002).

    Article  CAS  PubMed  Google Scholar 

  6. M. H. A. Elgamal, K. H. Shaker, K. Pollman, and K. Seifert, Phytochemistry, 40, 1233–1236 (1995).

    Article  CAS  Google Scholar 

  7. S. A. Sasmakov, Author’s Abstract of Master’s Thesis in Chemical Sciences, Tashkent 108

  8. S. A. Sasmakov, Zh. M. Putieva, and Z. Saatov, “Triterpene glycosides from Zygophyllum oxianum,” in: Young Scientists Conference on Organic Chemistry [in Russian], Ekaterinburg (2004).

  9. V. G. Baranov and I. M. Sokoloverova, Experimental Diabetes Mellitus: Role in Clinical Diabetology [in Russian], Meditsina, Leningrad (1983).

    Google Scholar 

  10. I. P. Zapadnyuk, V. I. Zapadnyuk, E. A. Zakhariya, and B. V. Zapadnyuk, Laboratory Animals: Rearing, Care, and Use in Experiments [in Russian], Vishcha Shkola, Kiev (1983).

  11. A. T. Karakashov and E. Vichev, Micromethods in Clinical Laboratory Practice [in Russian], Meditsina i Fizkul’tura, Sofia (1968).

  12. E. Barrent-Connor and A. Ferrara, Diabetes Care, 21, 1236–1239 (1998).

    Article  Google Scholar 

  13. J. Shaw, A. Hodge, M. De Courten, et al., Diabetologia, 354, 617–621 (1959).

    Google Scholar 

  14. M. D. Mashkovskii, Medicines [in Russian], RIA Novaya Volna, Moscow (2008), pp. 559–560.

  15. N. Kh. Yuldasheva, S. A. Sasmakov, and V. N. Syrov, in: Proceedings of the Conference “Current Problems in the Chemistry of Natural compounds [in Russian], Tashkent (2010).

  16. B. G. Katzung, Basic and Clinical Pharmacology [Russian translation], Binom-Nevskii Dialekt, Moscow, St. Petersburg (1998), Vol. 2.

Download references

Author information

Authors and Affiliations

  1. Academician S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, Uzbekistan

    N. Kh. Yuldasheva, S. A. Sasmakov, Z. A. Khushbaktova & V. N. Syrov

Authors
  1. N. Kh. Yuldasheva
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. A. Sasmakov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Z. A. Khushbaktova
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. V. N. Syrov
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 47, No. 8, pp. 37 – 40, August, 2013.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yuldasheva, N.K., Sasmakov, S.A., Khushbaktova, Z.A. et al. A Total Triterpene Glycosides Preparation from Zygophyllum Oxianum as a Potential Hypoglycemic Agent. Pharm Chem J 47, 433–436 (2013). https://doi.org/10.1007/s11094-013-0975-5

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11094-013-0975-5

Keywords

Search

Navigation