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Application of a chromatographic column with a diol sorbent for the analysis of platinum coordination compounds

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Pharmaceutical Chemistry Journal Aims and scope

It was found that a Nucleosil 100-5 OH column could be used for the analysis of platinum(II) coordination compounds. Use of mobile phases of CH3CN:H2O mixtures in ratios from 95:5 to 85:15 separated Pt(II) coordination compounds on chromatographic columns with diol and amine phases through a normal-phase mechanism.

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Authors and Affiliations

  1. State Scientific Center for Drug Expertise and Control, Ministry of the Russian Federation for Public Health and Social Development, Russian Federation, Moscow, Russia

    A. S. Osipov, E. B. Nechaeva & O. A. Pobedin

Authors
  1. A. S. Osipov
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  2. E. B. Nechaeva
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  3. O. A. Pobedin
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Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 47, No. 6, pp. 51 – 53, June, 2013.

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Osipov, A.S., Nechaeva, E.B. & Pobedin, O.A. Application of a chromatographic column with a diol sorbent for the analysis of platinum coordination compounds. Pharm Chem J 47, 337–339 (2013). https://doi.org/10.1007/s11094-013-0956-8

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  • DOI: https://doi.org/10.1007/s11094-013-0956-8

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