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Synthesis and Antimicrobial Activity of 2-Chloro(bromo)-(2-methyl)-3-arylpropionamides

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Pharmaceutical Chemistry Journal Aims and scope

2-Chloro(bromo)-(2-methyl)-3-arylpropanamides exhibited low antimicrobial activity with respect to strains of staphylococci, intestinal rods, aerobic bacilli, and yeast fungi. Introduction of pharmacophores into the aromatic ring did not increase significantly the antibacterial and antifungal activity of these compounds.

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Authors and Affiliations

  1. V. Hnatiuk Ternopil National Pedagogical University, Ternopil, Ukraine

    B. D. Grishchuk, R. V. Symchak & V. S. Baranovskii

  2. I. Ya. Horbachevsky Ternopil State Medical University, Ternopil, Ukraine

    S. I. Klimnyuk & E. V. Pokryshko

Authors
  1. B. D. Grishchuk
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  2. R. V. Symchak
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  3. V. S. Baranovskii
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  4. S. I. Klimnyuk
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  5. E. V. Pokryshko
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Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 47, No. 6, pp. 22 – 24, June, 2013.

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Grishchuk, B.D., Symchak, R.V., Baranovskii, V.S. et al. Synthesis and Antimicrobial Activity of 2-Chloro(bromo)-(2-methyl)-3-arylpropionamides. Pharm Chem J 47, 307–309 (2013). https://doi.org/10.1007/s11094-013-0949-7

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  • DOI: https://doi.org/10.1007/s11094-013-0949-7

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