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Synthesis and antioxidant activity of [(1-aryl-5-formylimidazol-4-yl)thio]acetic acids

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A series of [(1-aryl-5-formylimidazol-4-yl)thio]acetic acids were synthesized by condensation of 1-aryl-4-chloroimidazol-5-carbaldehydes with thioglycolic acid. The obtained compounds exhibited pronounced antioxidant activity in the concentration range 10 –1 – 10–3 M.

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Authors and Affiliations

  1. Bukovinian State Medical University, 58000, Chernovtsy, Ukraine

    V. A. Chornous, A. A. Palamar & I. N. Yaremii

  2. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 02660, Kiev, Ukraine

    I. N. Yaremii & M. V. Vovk

Authors
  1. V. A. Chornous
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  2. A. A. Palamar
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  3. I. N. Yaremii
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  4. M. V. Vovk
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Corresponding author

Correspondence to V. A. Chornous.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 47, No. 2, pp. 28 – 30, February, 2013.

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Chornous, V.A., Palamar, A.A., Yaremii, I.N. et al. Synthesis and antioxidant activity of [(1-aryl-5-formylimidazol-4-yl)thio]acetic acids. Pharm Chem J 47, 96–98 (2013). https://doi.org/10.1007/s11094-013-0903-8

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  • DOI: https://doi.org/10.1007/s11094-013-0903-8

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