A series of 3-spiro[adamantane-2,3′-isoquinolines] were synthesized. Their neurotropic activity and cytotoxicity were evaluated. Two compounds with anxiolytic activity were found, one of which showed antitumor activity in vitro.
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Translated from Khimiko-farmatsevticheskii Zhurnal, Vol. 46, No. 12, pp. 11–14, December, 2012.
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Anikina, L.V., Vikharev, Y.B., Rozhkova, Y.S. et al. Synthesis and Biological Activity of 3-Spiro[adamantane-2,3′-isoquinolines]. Pharm Chem J 46, 707–710 (2013). https://doi.org/10.1007/s11094-013-0874-9
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DOI: https://doi.org/10.1007/s11094-013-0874-9