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Pharmaceutical Chemistry Journal

, Volume 46, Issue 11, pp 672–675 | Cite as

Chemical composition of Allium schoenoprasum leaves and inhibitory effect of their extract on tumor growth in mice

  • T. I. Shirshova
  • I. V. Beshlei
  • V. P. Deryagina
  • N. I. Ryzhova
  • N. V. Matistov
Medicinal Plants

A comprehensive chemical study of the cultivated plant Allium schoenoprasum L. from the collection of the Botanical Garden of the Institute of Biology (Komi Scientific Center, UB, RAS) showed that its leaves contained a wide range of biologically active substances and trace elements involved in the antioxidant and anticarcinogenic protection system of humans. An experiment for the evaluation of the antitumor potential of these substances showed that the aqueous and aqueous-alcohol extracts of onion leaves tended to inhibit the growth of subcutaneously grafted Ehrlich carcinoma in male BDF mice at the stage of intense tumor development.

Keywords

A. schoenoprasum L. extract anticarcinogenic effect 

Notes

Acknowledgments

The work was supported by the Ural Branch, RAS, Basic Research Program “Accumulating Properties of Several Representatives of the Genus Allium L. for Selenium and Creation of Pharmacological Compositions with Antioxidant and Antitumor Activity Based on Them,” Project No. 12-U-4 – 1016.

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • T. I. Shirshova
    • 1
  • I. V. Beshlei
    • 1
  • V. P. Deryagina
    • 2
  • N. I. Ryzhova
    • 2
  • N. V. Matistov
    • 1
  1. 1.Institute of Biology, Komi Scientific Center, Ural BranchRussian Academy of SciencesSyktyvkarRussia
  2. 2.Research Institute of Carcinogenesis, Blokhin Russian Oncological Research CenterRussian Academy of Medical SciencesMoscowRussia

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