The polyphenol complex (maksar) from the Far-Eastern tree Maackia amurensis and its phenolic constituents were tested for their ability to (1) scavenge 2,2-diphenyl-1-picrylhydrazyl radicals (DPPH), (2) reduce Folin—Ciocalteau reagent (FCR), (3) reduce radical cations of 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid (ABTS∙+), and (4) inhibit peroxide-induced oxidation of linoleic acid (LA). It was established that the main components of maksar that contribute to the antioxidant potential of the polyphenol complex were the stilbenes resveratrol, piceatannol, scirpusin A, scirpusin B, maackiazine, and maackoline; the isoflavonoids retusin, tectorigenin, and genistein, and the minor isoflavonoids calycosin and vestitol, the stilbene dihydroresveratrol, and the chalcones isoliquiritigenin and α,2′,4′,4-tetrahydroxydihydrochalcone.
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Acknowledgments
The work was supported by grants 11-04-00770 (RFBR), 09-III-A-05-145 (FEB, RAS), and the RAS Presidium Program Molecular and Cellular Biology.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 46, No. 8, pp. 23 – 26, August, 2012.
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Utkina, N.K., Kulesh, N.I. Antioxidant activity of polyphenols and polyphenol complex from the far-eastern tree Maackia amurensis. Pharm Chem J 46, 488–491 (2012). https://doi.org/10.1007/s11094-012-0831-z
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DOI: https://doi.org/10.1007/s11094-012-0831-z