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Effect of Echinacea purpurea tincture on the rat kidney antioxidant system under carbon tetrachloride intoxication

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The influence of Echinacea purpurea tincture on the state of rat kidney antioxidant system under carbon tetrachloride intoxication was studied. It was established that the content of TBA reaction products increased, the activity of catalase and glutathione transferase decreased, and the reduced glutathione level and the glutathione peroxidase activity increased in kidney supernatants from rats intoxicated with carbon tetrachloride. Administration of E. purpurea tincture for 5 d after carbon tetrachloride intoxication restored the glutathione peroxidase activity and corrected other antioxidant system parameters in rat kidneys.

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Authors and Affiliations

  1. Bukovinian State Medical University, Chernivtsi, Ukraine

    I. V. Matsiopa, N. F. Grigor’eva & I. F. Meshchyshen

Authors
  1. I. V. Matsiopa
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  2. N. F. Grigor’eva
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  3. I. F. Meshchyshen
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Correspondence to I. V. Matsiopa.

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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 46, No. 7, pp. 37 – 38, July, 2012.

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Matsiopa, I.V., Grigor’eva, N.F. & Meshchyshen, I.F. Effect of Echinacea purpurea tincture on the rat kidney antioxidant system under carbon tetrachloride intoxication. Pharm Chem J 46, 441–442 (2012). https://doi.org/10.1007/s11094-012-0817-x

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  • DOI: https://doi.org/10.1007/s11094-012-0817-x

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