Micellar electrokinetic chromatography was used to determine the content of indole-3-carbinol in aerial parts of some plants from the family Brassicaceae. It was established that the herb of Brassica napus L. and the leaves of Brassica rapa L. had high contents of indole-3-carbinol (from 1.4 to 1.9%). In view of the potential use of Brassica napus as a source of anticancer compounds, reversed-phase HPLC was performed and revealed a significant content of flavonoids with the major aglycons quercetin, kaempferol, and isorhamnetin.
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References
Vestn. Nauchno-Issled. Inst. Mol. Med., No. 9, 49 – 56 (2009).
P. A. Apukhtin, O. I. Anashkina, and D. N. Sidorin, Farmatsiya, No. 5, 52 – 54 (2009).
K.-I. Jeon, J.-K. Rih, et al., FEBS Lett., 544, 246 – 251 (2003).
P. H. Jellinck and P. Gekforkert, Biochem. Pharmacol., 45, 1129 – 1136 (1993).
F. Kassie, S. Kalscheuer, et al., Carcinogenesis, 31(2), 239 – 245 (2010).
A. Ahmad,W. A. Sakr, and K. M. Rahman, Curr. Drug Targets, 11(6), 652 – 666 (2010).
A. Baumert, C. Milkowski, et al., Phytochemistry, 66(11), 1334 – 1345 (2005).
K. Sasaki and T. Takahashi, Phytochemistry, 61(5), 339 – 343 (2002).
A. B. Durkeet and J. B. Harborne, Phytochemistry, 12(5), 1085 – 1089 (1973).
M. A. Susan Marles, M. Y. Gruber, G. J. Scoles, and A. D. Muir, Phytochemistry, 62(2), 663 – 672 (2003).
G. Hrazdina, R. Alscher-Herman, and V. M. Kish, Phytochemistry, 19(7), 1355 – 1359 (1980).
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 46, No. 6, pp. 32 – 35, June, 2012.
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Gavrilin, M.V., Sedin, A.V. & Senchenko, S.P. Quantitative determination of anticancer compounds in aerial parts of some plants from the family brassicaceae. Pharm Chem J 46, 360–362 (2012). https://doi.org/10.1007/s11094-012-0798-9
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DOI: https://doi.org/10.1007/s11094-012-0798-9