An alternative efficient road for the synthesis of 16α,17α-epoxy-pregn-4,9(11)-dien-21-ol-3,20-dione from 9α-hydroxy-androst-4-ene-3,17-dione via its Δ9-analog has been studied.
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One of the authors (L. D. H.) gratefully acknowledges support from the National Foundation for Science and Technology Development (grant no. 104.01.50.09).
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Huy, L.D., Diep, N.T. & Nhung, L.T.K. Alternative road for synthesis of 16α,17α-epoxy-pregn-4,9(11)-dien-21-OL-3,20-dione from 9α-hydroxy-androstenedione. Pharm Chem J 46, 356–359 (2012). https://doi.org/10.1007/s11094-012-0797-x
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DOI: https://doi.org/10.1007/s11094-012-0797-x