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Specific features of drug encapsulation in liposomes (A review)

  • Drug Synthesis Methods and Manufacturing Technology
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Pharmaceutical Chemistry Journal Aims and scope

Liposomes are hollow particles, the internal space of which is bounded by a lipid membrane. Liposomes are promising drug delivery systems for organs and tissues because of their colloidal properties, controlled size, surface characteristics, membrane action, and biocompatibility. Liposomal drugs have found wide use in the diagnosis and chemotherapy of cancer, vaccinology, ophthalmology, pulmonology, and the treatment of other pathologies. This review describes the methods of encapsulation of biologically active compounds with various physicochemical properties in liposomes, which is very important for the production of liposomal drugs.

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Authors and Affiliations

  1. Blokhin Oncological Center, Russian Academy of Medical Sciences, Moscow, Russia

    E. V. Tazina, K. V. Kostin & N. A. Oborotova

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  1. E. V. Tazina
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  2. K. V. Kostin
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  3. N. A. Oborotova
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 45, No. 8, pp. 30 – 40, August, 2011.

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Tazina, E.V., Kostin, K.V. & Oborotova, N.A. Specific features of drug encapsulation in liposomes (A review). Pharm Chem J 45, 481–490 (2011). https://doi.org/10.1007/s11094-011-0661-4

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  • DOI: https://doi.org/10.1007/s11094-011-0661-4

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