A series of 2-arylaminonicotinic acid β-(3-carboxypropionyl)hydrazides were synthesized by the reaction of 2-arylaminonicotinic acids with succinic anhydride. All of the synthesized compounds possess weak antimicrobial properties. Three compounds exhibit an anticoagulant effect.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 45, No. 8, pp. 26 – 27, August, 2011.
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Kon’shin, M.E., Syropyatov, B.Y., Efremov, A.L. et al. Synthesis and pharmacological activity of 2-arylaminonicotinic acid β-(3-carboxypropionyl)hydrazides. Pharm Chem J 45, 472–473 (2011). https://doi.org/10.1007/s11094-011-0658-z
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DOI: https://doi.org/10.1007/s11094-011-0658-z